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Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases

Overview of attention for article published in Journal of Translational Medicine, March 2013
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Title
Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases
Published in
Journal of Translational Medicine, March 2013
DOI 10.1186/1479-5876-11-70
Pubmed ID
Authors

Jian Zhong Qin, Vivek Upadhyay, Bellur Prabhakar, Ajay V Maker

Abstract

T-cell infiltration in primary colon tumors is associated with improved patient survival. Preliminary data supports a similar association in colorectal liver metastases (CRLM), and we previously identified increased CRLM expression of the immunostimulatory cytokine LIGHT (TNFSF14) to be related to improved patient prognosis. Therefore, mechanisms to augment the T-cell response in CRLM may be a promising treatment modality, however, the tumor immune microenvironment and LIGHT expression in CRLM remains to be characterized.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Austria 1 2%
Unknown 55 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 30%
Student > Ph. D. Student 9 16%
Student > Doctoral Student 6 11%
Student > Master 6 11%
Other 3 5%
Other 7 12%
Unknown 9 16%
Readers by discipline Count As %
Immunology and Microbiology 16 28%
Agricultural and Biological Sciences 13 23%
Medicine and Dentistry 10 18%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 1 2%
Other 2 4%
Unknown 11 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2013.
All research outputs
#15,270,698
of 22,708,120 outputs
Outputs from Journal of Translational Medicine
#2,230
of 3,970 outputs
Outputs of similar age
#123,603
of 197,463 outputs
Outputs of similar age from Journal of Translational Medicine
#41
of 57 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,970 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,463 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.