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A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products

Overview of attention for article published in Malaria Journal, April 2013
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2 X users

Citations

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Title
A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products
Published in
Malaria Journal, April 2013
DOI 10.1186/1475-2875-12-145
Pubmed ID
Authors

Sultan Suleman, Kirsten Vandercruyssen, Evelien Wynendaele, Matthias D’Hondt, Nathalie Bracke, Luc Duchateau, Christian Burvenich, Kathelijne Peremans, Bart De Spiegeleer

Abstract

Artemisinin-based fixed dose combination (FDC) products are recommended by World Health Organization (WHO) as a first-line treatment. However, the current artemisinin FDC products, such as β-artemether and lumefantrine, are inherently unstable and require controlled distribution and storage conditions, which are not always available in resource-limited settings. Moreover, quality control is hampered by lack of suitable analytical methods. Thus, there is a need for a rapid and simple, but stability-indicating method for the simultaneous assay of β-artemether and lumefantrine FDC products.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ireland 1 2%
Ghana 1 2%
Belgium 1 2%
Unknown 57 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 23%
Student > Master 11 18%
Researcher 7 12%
Student > Doctoral Student 6 10%
Lecturer 2 3%
Other 7 12%
Unknown 13 22%
Readers by discipline Count As %
Medicine and Dentistry 13 22%
Chemistry 10 17%
Pharmacology, Toxicology and Pharmaceutical Science 9 15%
Agricultural and Biological Sciences 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 7 12%
Unknown 14 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2013.
All research outputs
#17,687,135
of 22,708,120 outputs
Outputs from Malaria Journal
#4,831
of 5,545 outputs
Outputs of similar age
#138,069
of 192,344 outputs
Outputs of similar age from Malaria Journal
#66
of 76 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,545 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,344 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.