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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau
|
|---|---|
| Published in |
Translational Neurodegeneration, October 2012
|
| DOI | 10.1186/2047-9158-1-21 |
| Pubmed ID | |
| Authors |
Yang Hong-Qi, Sun Zhi-Kun, Chen Sheng-Di |
| Abstract |
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mainly the memory and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau hyperphosphorylation are the two pathological events that are thought to cause neuronal dysfunction in AD. Since the detailed mechanisms that underlie the pathogenesis of AD are still not clear, the current treatments are those drugs that can alleviate the symptoms of AD patients. Recent studies have indicated that these symptom-reliving drugs also have the ability of regulating amyloid precursor protein processing and tau phosphorylation. Thus the pharmacological mechanism of these drugs may be too simply-evaluated. This review summarizes the current status of AD therapy and some potential preclinical considerations that target beta amyloid and tau protein are also discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| Czechia | 1 | <1% |
| United Kingdom | 1 | <1% |
| Mexico | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 178 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 38 | 21% |
| Student > Ph. D. Student | 36 | 20% |
| Researcher | 23 | 13% |
| Student > Bachelor | 16 | 9% |
| Student > Postgraduate | 14 | 8% |
| Other | 28 | 15% |
| Unknown | 29 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 25% |
| Medicine and Dentistry | 25 | 14% |
| Chemistry | 21 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 10% |
| Biochemistry, Genetics and Molecular Biology | 14 | 8% |
| Other | 26 | 14% |
| Unknown | 34 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2018.
All research outputs
#2,329,708
of 25,373,627 outputs
Outputs from Translational Neurodegeneration
#81
of 384 outputs
Outputs of similar age
#16,279
of 202,126 outputs
Outputs of similar age from Translational Neurodegeneration
#1
of 4 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,126 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them