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A methodology for detecting the orthology signal in a PPI network at a functional complex level

Overview of attention for article published in BMC Bioinformatics, June 2012
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Title
A methodology for detecting the orthology signal in a PPI network at a functional complex level
Published in
BMC Bioinformatics, June 2012
DOI 10.1186/1471-2105-13-s10-s18
Pubmed ID
Authors

Pavol Jancura, Eleftheria Mavridou, Enrique Carrillo-de Santa Pau, Elena Marchiori

Abstract

Stable evolutionary signal has been observed in a yeast protein-protein interaction (PPI) network. These finding suggests more connected regions of a PPI network to be potential mediators of evolutionary information. Because more connected regions of PPI networks contain functional complexes, we are motivated to exploit the orthology relation for identifying complexes that can be clearly attributed to such evolutionary signal.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 5%
United States 1 5%
Germany 1 5%
Brazil 1 5%
Unknown 16 80%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 35%
Student > Ph. D. Student 4 20%
Lecturer 1 5%
Student > Doctoral Student 1 5%
Student > Bachelor 1 5%
Other 5 25%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 40%
Computer Science 6 30%
Biochemistry, Genetics and Molecular Biology 2 10%
Medicine and Dentistry 1 5%
Unknown 3 15%