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Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

Overview of attention for article published in BMC Biology, January 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

blogs
1 blog

Citations

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103 Dimensions

Readers on

mendeley
36 Mendeley
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Title
Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling
Published in
BMC Biology, January 2008
DOI 10.1186/1741-7007-6-1
Pubmed ID
Authors

Tetsuya Okajima, BVVG Reddy, Tsukasa Matsuda, Kenneth D Irvine

Abstract

O-fucosyltransferase1 (OFUT1) is a conserved ER protein essential for Notch signaling. OFUT1 glycosylates EGF domains, which can then be further modified by the N-acetylglucosaminyltransferase Fringe. OFUT1 also possesses a chaperone activity that promotes the folding and secretion of Notch. Here, we investigate the respective contributions of these activities to Notch signaling in Drosophila.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
China 1 3%
Brazil 1 3%
Unknown 33 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 39%
Researcher 9 25%
Professor 3 8%
Other 2 6%
Student > Bachelor 2 6%
Other 5 14%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 50%
Biochemistry, Genetics and Molecular Biology 14 39%
Chemistry 2 6%
Business, Management and Accounting 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2009.
All research outputs
#527,964
of 3,685,758 outputs
Outputs from BMC Biology
#267
of 579 outputs
Outputs of similar age
#15,123
of 85,555 outputs
Outputs of similar age from BMC Biology
#21
of 36 outputs
Altmetric has tracked 3,685,758 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 579 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 85,555 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.