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Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

Overview of attention for article published in Journal of Neuroinflammation, May 2013
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Title
Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice
Published in
Journal of Neuroinflammation, May 2013
DOI 10.1186/1742-2094-10-54
Pubmed ID
Authors

Marcus A Lawson, Robert H McCusker, Keith W Kelley

Abstract

Interleukin-1 beta converting enzyme (ICE, caspase 1) is a cysteine protease that processes immature pro-IL-1β into active mature IL-1β. IL-1β is a pro-inflammatory cytokine that mediates many of the physiological and behavioral responses to inflammation. Genetic deletion of ICE has previously been shown to prevent some negative physiologic responses to lipopolysaccharide (LPS)-induced inflammation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 83 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 18%
Student > Bachelor 14 17%
Researcher 13 15%
Student > Master 12 14%
Professor > Associate Professor 4 5%
Other 6 7%
Unknown 20 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 20%
Biochemistry, Genetics and Molecular Biology 8 10%
Neuroscience 8 10%
Medicine and Dentistry 7 8%
Psychology 7 8%
Other 15 18%
Unknown 22 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2013.
All research outputs
#15,271,180
of 22,709,015 outputs
Outputs from Journal of Neuroinflammation
#1,735
of 2,612 outputs
Outputs of similar age
#119,345
of 192,823 outputs
Outputs of similar age from Journal of Neuroinflammation
#16
of 30 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,612 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,823 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.