RT @interactivefly: Perez-Moreno, J. J., Smith, R. C., Oliva, M. K., Gallo, F., Ojha, S., Muller, K. H. and O'Kane, C. J. (2023). Drosophil…
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Perez-Moreno, J. J., Smith, R. C., Oliva, M. K., Gallo, F., Ojha, S., Muller, K. H. and O'Kane, C. J. (2023). Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics. J Cell Biol 222(6). https://t.co/zHDmD81fa7
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@RahmanLab Wow! This could maybe explain findings Anne Willis & colleagues @MRC_TU that ER-shaping protein RTN3 mediates protection from cold-shock? Our work suggests that loss of reticulon Rtnl1 in flies may reduce STIM signaling at Drosophila synapse
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RT @JCellBiol: Reduced ER tubules & calcium flux in #Drosophila motor terminals lacking the SPG12/RTN2 ortholog Rtnl1. From @jjperezmoreno…