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Host-mediated RNA editing in viruses

Overview of attention for article published in Biology Direct, March 2023
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Average Attention Score compared to outputs of the same age and source

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Title
Host-mediated RNA editing in viruses
Published in
Biology Direct, March 2023
DOI 10.1186/s13062-023-00366-w
Pubmed ID
Authors

Tongtong Zhu, Guangyi Niu, Yuansheng Zhang, Ming Chen, Chuan-Yun Li, Lili Hao, Zhang

Abstract

Viruses rely on hosts for life and reproduction, cause a variety of symptoms from common cold to AIDS to COVID-19 and provoke public health threats claiming millions of lives around the globe. RNA editing, as a crucial co-/post-transcriptional modification inducing nucleotide alterations on both endogenous and exogenous RNA sequences, exerts significant influences on virus replication, protein synthesis, infectivity and toxicity. Hitherto, a number of host-mediated RNA editing sites have been identified in diverse viruses, yet lacking a full picture of RNA editing-associated mechanisms and effects in different classes of viruses. Here we synthesize the current knowledge of host-mediated RNA editing in a variety of viruses by considering two enzyme families, viz., ADARs and APOBECs, thereby presenting a landscape of diverse editing mechanisms and effects between viruses and hosts. In the ongoing pandemic, our study promises to provide potentially valuable insights for better understanding host-mediated RNA editing on ever-reported and newly-emerging viruses.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 27%
Student > Doctoral Student 2 18%
Researcher 1 9%
Student > Ph. D. Student 1 9%
Student > Master 1 9%
Other 0 0%
Unknown 3 27%
Readers by discipline Count As %
Unspecified 3 27%
Biochemistry, Genetics and Molecular Biology 2 18%
Immunology and Microbiology 1 9%
Engineering 1 9%
Unknown 4 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2023.
All research outputs
#14,461,056
of 24,674,524 outputs
Outputs from Biology Direct
#314
of 523 outputs
Outputs of similar age
#172,941
of 406,724 outputs
Outputs of similar age from Biology Direct
#7
of 13 outputs
Altmetric has tracked 24,674,524 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 523 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,724 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.