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The Role of Inflammation in the Initiation and Progression of Myeloid Neoplasms

Overview of attention for article published in Blood Cancer Discovery, April 2023
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#27 of 187)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

twitter
107 tweeters

Citations

dimensions_citation
1 Dimensions

Readers on

mendeley
14 Mendeley
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Title
The Role of Inflammation in the Initiation and Progression of Myeloid Neoplasms
Published in
Blood Cancer Discovery, April 2023
DOI 10.1158/2643-3230.bcd-22-0176
Pubmed ID
Authors

Juan Carlos Balandrán, Audrey Lasry, Iannis Aifantis

Abstract

Myeloid malignancies are devastating hematologic cancers with limited therapeutic options. Inflammation is emerging as a novel driver of myeloid malignancy, with important implications for tumor composition, immune response, therapeutic options, and patient survival. Here, we discuss the role of inflammation in normal and malignant hematopoiesis, from clonal hematopoiesis to full-blown myeloid leukemia. We discuss how inflammation shapes clonal output from hematopoietic stem cells, how inflammation alters the immune microenvironment in the bone marrow, and novel therapies aimed at targeting inflammation in myeloid disease. Inflammation is emerging as an important factor in myeloid malignancies. Understanding the role of inflammation in myeloid transformation, and the interplay between inflammation and other drivers of leukemogenesis, may yield novel avenues for therapy.

Twitter Demographics

Twitter Demographics

The data shown below were collected from the profiles of 107 tweeters who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 21%
Researcher 3 21%
Student > Ph. D. Student 2 14%
Student > Bachelor 1 7%
Student > Master 1 7%
Other 1 7%
Unknown 3 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 36%
Medicine and Dentistry 2 14%
Immunology and Microbiology 1 7%
Unknown 6 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 64. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2023.
All research outputs
#633,612
of 24,518,979 outputs
Outputs from Blood Cancer Discovery
#27
of 187 outputs
Outputs of similar age
#13,676
of 401,992 outputs
Outputs of similar age from Blood Cancer Discovery
#4
of 11 outputs
Altmetric has tracked 24,518,979 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 187 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.5. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 401,992 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.