Title |
Advanced paternal age is a risk factor for schizophrenia in Iranians
|
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Published in |
Annals of General Psychiatry, April 2011
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DOI | 10.1186/1744-859x-10-15 |
Pubmed ID | |
Authors |
Morteza Naserbakht, Hamid-Reza Ahmadkhaniha, Bahareh Mokri, Cassandra L Smith |
Abstract |
Since 1958 many, but not all studies have demonstrated that paternal age is a risk factor for schizophrenia. There may be many different explanations for differences between studies, including study design, sample size, collection criteria, heterogeneity and the confounding effects of environmental factors that can for example perturb epigenetic programming and lead to an increase in disease risk. The small number of children in Western families makes risk comparisons between siblings born at different paternal ages difficult. In contrast, more Eastern families have children both at early and later periods of life. In the present study, a cross-sectional population study in an Iranian population was performed to compare frequency of schizophrenia in younger offspring (that is, older paternal age) versus older offspring. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Chile | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Iceland | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 15% |
Student > Master | 9 | 15% |
Researcher | 8 | 13% |
Student > Doctoral Student | 6 | 10% |
Student > Bachelor | 4 | 6% |
Other | 11 | 18% |
Unknown | 15 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 24% |
Psychology | 8 | 13% |
Biochemistry, Genetics and Molecular Biology | 5 | 8% |
Agricultural and Biological Sciences | 3 | 5% |
Neuroscience | 3 | 5% |
Other | 10 | 16% |
Unknown | 18 | 29% |