Title |
Slower immune system aging in women versus men in the Japanese population
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Published in |
Immunity & Ageing, May 2013
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DOI | 10.1186/1742-4933-10-19 |
Pubmed ID | |
Authors |
Katsuiku Hirokawa, Masanori Utsuyama, Yoshio Hayashi, Masanobu Kitagawa, Takashi Makinodan, Tamas Fulop |
Abstract |
Gender-related differences in humans are commonly observed in behaviour, physical activity, disease, and lifespan. However, the notion that age-related changes in the immune system differ between men and women remains controversial. To elucidate the relationship between immunological changes and lifespan, peripheral blood mononuclear cells from healthy Japanese subjects (age range: 20-90 years; N = 356) were analysed by using three-colour flow cytometry. The proliferative activities and cytokine-producing capacities of T cells in response to anti-CD3 monoclonal antibody stimulation were also assessed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 18% |
United Kingdom | 3 | 14% |
Canada | 2 | 9% |
Belgium | 1 | 5% |
Indonesia | 1 | 5% |
Switzerland | 1 | 5% |
Taiwan | 1 | 5% |
Unknown | 9 | 41% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 14 | 64% |
Practitioners (doctors, other healthcare professionals) | 3 | 14% |
Science communicators (journalists, bloggers, editors) | 3 | 14% |
Scientists | 2 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Germany | 1 | <1% |
France | 1 | <1% |
Mozambique | 1 | <1% |
Israel | 1 | <1% |
Norway | 1 | <1% |
Unknown | 120 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 20 | 16% |
Student > Ph. D. Student | 18 | 14% |
Researcher | 18 | 14% |
Student > Master | 15 | 12% |
Student > Postgraduate | 6 | 5% |
Other | 16 | 13% |
Unknown | 34 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 25 | 20% |
Medicine and Dentistry | 20 | 16% |
Immunology and Microbiology | 13 | 10% |
Biochemistry, Genetics and Molecular Biology | 11 | 9% |
Neuroscience | 4 | 3% |
Other | 15 | 12% |
Unknown | 39 | 31% |