Title |
Co-occurrence of anaerobic bacteria in colorectal carcinomas
|
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Published in |
Microbiome, May 2013
|
DOI | 10.1186/2049-2618-1-16 |
Pubmed ID | |
Authors |
René L Warren, Douglas J Freeman, Stephen Pleasance, Peter Watson, Richard A Moore, Kyla Cochrane, Emma Allen-Vercoe, Robert A Holt |
Abstract |
Numerous cancers have been linked to microorganisms. Given that colorectal cancer is a leading cause of cancer deaths and the colon is continuously exposed to a high diversity of microbes, the relationship between gut mucosal microbiome and colorectal cancer needs to be explored. Metagenomic studies have shown an association between Fusobacterium species and colorectal carcinoma. Here, we have extended these studies with deeper sequencing of a much larger number (n = 130) of colorectal carcinoma and matched normal control tissues. We analyzed these data using co-occurrence networks in order to identify microbe-microbe and host-microbe associations specific to tumors. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 38% |
United States | 1 | 13% |
Sweden | 1 | 13% |
Malaysia | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 1% |
Germany | 2 | <1% |
United Kingdom | 2 | <1% |
France | 1 | <1% |
Sweden | 1 | <1% |
India | 1 | <1% |
Estonia | 1 | <1% |
Canada | 1 | <1% |
Unknown | 284 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 65 | 22% |
Student > Ph. D. Student | 51 | 17% |
Student > Bachelor | 35 | 12% |
Student > Master | 27 | 9% |
Student > Doctoral Student | 14 | 5% |
Other | 44 | 15% |
Unknown | 60 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 75 | 25% |
Biochemistry, Genetics and Molecular Biology | 63 | 21% |
Medicine and Dentistry | 33 | 11% |
Immunology and Microbiology | 29 | 10% |
Engineering | 7 | 2% |
Other | 24 | 8% |
Unknown | 65 | 22% |