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Modern Proteomics – Sample Preparation, Analysis and Practical Applications

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Cover of 'Modern Proteomics – Sample Preparation, Analysis and Practical Applications'

Table of Contents

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    Book Overview
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    Chapter 1 Proteomes, Their Compositions and Their Sources
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    Chapter 2 Protein Fractionation and Enrichment Prior to Proteomics Sample Preparation
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    Chapter 3 Sample Preparation for Mass Spectrometry-Based Proteomics; from Proteomes to Peptides
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    Chapter 4 Plant Structure and Specificity – Challenges and Sample Preparation Considerations for Proteomics
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    Chapter 5 Improving Proteome Coverage by Reducing Sample Complexity via Chromatography
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    Chapter 6 Database Search Engines: Paradigms, Challenges and Solutions
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    Chapter 7 Mass Analyzers and Mass Spectrometers
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    Chapter 8 Top-Down Mass Spectrometry: Proteomics to Proteoforms
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    Chapter 9 Platforms and Pipelines for Proteomics Data Analysis and Management
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    Chapter 10 Tandem Mass Spectrum Sequencing: An Alternative to Database Search Engines in Shotgun Proteomics
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    Chapter 11 Visualization, Inspection and Interpretation of Shotgun Proteomics Identification Results
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    Chapter 12 Protein Inference
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    Chapter 13 Modification Site Localization in Peptides
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    Chapter 14 Useful Web Resources
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    Chapter 15 Mass Spectrometry-Based Protein Quantification
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    Chapter 16 Bioinformatics Tools for Proteomics Data Interpretation
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    Chapter 17 Identification, Quantification, and Site Localization of Protein Posttranslational Modifications via Mass Spectrometry-Based Proteomics
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    Chapter 18 Protein-Protein Interaction Detection Via Mass Spectrometry-Based Proteomics
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    Chapter 19 Protein Structural Analysis via Mass Spectrometry-Based Proteomics
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    Chapter 20 Introduction to Clinical Proteomics
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    Chapter 21 Discovery of Candidate Biomarkers
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    Chapter 22 Statistical Approaches to Candidate Biomarker Panel Selection
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    Chapter 23 Qualification and Verification of Protein Biomarker Candidates
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    Chapter 24 Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments Through an MRM-with-Standard-Peptides Quantitative Approach
Attention for Chapter 12: Protein Inference
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Citations

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Chapter title
Protein Inference
Chapter number 12
Book title
Modern Proteomics – Sample Preparation, Analysis and Practical Applications
Published in
Advances in experimental medicine and biology, December 2016
DOI 10.1007/978-3-319-41448-5_12
Pubmed ID
Book ISBNs
978-3-31-941446-1, 978-3-31-941448-5
Authors

Zengyou He, Ting Huang, Can Zhao, Ben Teng

Editors

Hamid Mirzaei, Martin Carrasco

Abstract

Protein inference is one of the most important steps in protein identification, which transforms peptides identified from tandem mass spectra into a list of proteins. In this chapter, we provide a brief introduction on this problem and present a short summary on the existing protein inference methods in the literature.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 38%
Professor > Associate Professor 2 25%
Other 2 25%
Unknown 1 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 50%
Computer Science 1 13%
Agricultural and Biological Sciences 1 13%
Unknown 2 25%