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Numerical investigation of the effect of cannula placement on thrombosis

Overview of attention for article published in Theoretical Biology and Medical Modelling, January 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)

Mentioned by

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4 tweeters

Citations

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22 Dimensions

Readers on

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42 Mendeley
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Title
Numerical investigation of the effect of cannula placement on thrombosis
Published in
Theoretical Biology and Medical Modelling, January 2013
DOI 10.1186/1742-4682-10-35
Pubmed ID
Authors

ChiWei Ong, Socrates Dokos, BeeTing Chan, Einly Lim, Amr Abed, Noor Azuan Bin Abu Osman, Suhaini Kadiman, Nigel H Lovell

Abstract

Despite the rapid advancement of left ventricular assist devices (LVADs), adverse events leading to deaths have been frequently reported in patients implanted with LVADs, including bleeding, infection, thromboembolism, neurological dysfunction and hemolysis. Cannulation forms an important component with regards to thrombus formation in assisted patients by varying the intraventricular flow distribution in the left ventricle (LV). To investigate the correlation between LVAD cannula placement and potential for thrombus formation, detailed analysis of the intraventricular flow field was carried out in the present study using a two way fluid structure interaction (FSI), axisymmetric model of a passive LV incorporating an inflow cannula. Three different cannula placements were simulated, with device insertion near the LV apex, penetrating one-fourth and mid-way into the LV long axis. The risk of thrombus formation is assessed by analyzing the intraventricular vorticity distribution and its associated vortex intensity, amount of stagnation flow in the ventricle as well as the level of wall shear stress. Our results show that the one-fourth placement of the cannula into the LV achieves the best performance in reducing the risk of thrombus formation. Compared to cannula placement near the apex, higher vortex intensity is achieved at the one-fourth placement, thus increasing wash out of platelets at the ventricular wall. One-fourth LV penetration produced negligible stagnation flow region near the apical wall region, helping to reduce platelet deposition on the surface of the cannula and the ventricular wall.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 5%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 33%
Other 7 17%
Researcher 7 17%
Student > Master 4 10%
Student > Doctoral Student 3 7%
Other 5 12%
Unknown 2 5%
Readers by discipline Count As %
Engineering 27 64%
Medicine and Dentistry 6 14%
Agricultural and Biological Sciences 5 12%
Chemistry 1 2%
Unknown 3 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2013.
All research outputs
#6,783,180
of 12,516,972 outputs
Outputs from Theoretical Biology and Medical Modelling
#84
of 227 outputs
Outputs of similar age
#62,348
of 147,405 outputs
Outputs of similar age from Theoretical Biology and Medical Modelling
#1
of 1 outputs
Altmetric has tracked 12,516,972 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 227 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 147,405 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them