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Antiprotozoal and antimycobacterial activities of Persea americana seeds

Overview of attention for article published in BMC Complementary Medicine and Therapies, May 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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3 X users
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8 Facebook pages

Citations

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60 Dimensions

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175 Mendeley
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Title
Antiprotozoal and antimycobacterial activities of Persea americana seeds
Published in
BMC Complementary Medicine and Therapies, May 2013
DOI 10.1186/1472-6882-13-109
Pubmed ID
Authors

Adelina Jiménez-Arellanes, Julieta Luna-Herrera, Ricardo Ruiz-Nicolás, Jorge Cornejo-Garrido, Amparo Tapia, Lilián Yépez-Mulia

Abstract

BACKGROUND: Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites. METHODS: The chloroformic and ethanolic extracts of P. americana seeds were prepared by maceration and their amoebicidal, giardicidal and trichomonicidal activity was evaluated. These extracts were also tested against Mycobacterium tuberculosis H37Rv, four mono-resistant and two multidrug resistant strains of M. tuberculosis as well as five non tuberculosis mycobacterium strains by MABA assay. RESULTS: The chloroformic and ethanolic extracts of P. americana seeds showed significant activity against E. histolytica, G. lamblia and T. vaginalis (IC50 <0.634 mug/ml). The chloroformic extract inhibited the growth of M. tuberculosis H37Rv, M. tuberculosis MDR SIN 4 isolate, three M. tuberculosis H37Rv mono-resistant reference strains and four non tuberculosis mycobacteria (M. fortuitum, M. avium, M. smegmatis and M. absessus) showing MIC values <=50 mug/ml. Contrariwise, the ethanolic extract affected only the growth of two mono-resistant strains of M. tuberculosis H37Rv and M. smegmatis (MIC <=50 mug/ml). CONCLUSIONS: The CHCl3 and EtOH seed extracts from P. americana showed amoebicidal and giardicidal activity. Importantly, the CHCl3 extract inhibited the growth of a MDR M. tuberculosis isolate and three out of four mono-resistant reference strains of M. tuberculosis H37Rv, showing a MIC = 50 mug/ml. This extract was also active against the NTM strains, M. fortuitum, M. avium, M. smegmatis and M. abscessus, with MIC values <50 mug/ml.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 2 1%
Brazil 1 <1%
Colombia 1 <1%
Peru 1 <1%
United Kingdom 1 <1%
Unknown 169 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 32 18%
Student > Bachelor 29 17%
Researcher 16 9%
Student > Ph. D. Student 12 7%
Other 9 5%
Other 30 17%
Unknown 47 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 15%
Medicine and Dentistry 21 12%
Chemistry 17 10%
Biochemistry, Genetics and Molecular Biology 15 9%
Pharmacology, Toxicology and Pharmaceutical Science 13 7%
Other 27 15%
Unknown 55 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2023.
All research outputs
#7,783,721
of 24,178,331 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,238
of 3,796 outputs
Outputs of similar age
#64,748
of 198,221 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#30
of 69 outputs
Altmetric has tracked 24,178,331 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,796 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,221 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.