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The most transformative drugs of the past 25 years: a survey of physicians

Overview of attention for article published in Nature Reviews Drug Discovery, May 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
5 news outlets
policy
1 policy source
twitter
40 X users
facebook
3 Facebook pages

Citations

dimensions_citation
41 Dimensions

Readers on

mendeley
127 Mendeley
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Title
The most transformative drugs of the past 25 years: a survey of physicians
Published in
Nature Reviews Drug Discovery, May 2013
DOI 10.1038/nrd3977
Pubmed ID
Authors

Aaron S. Kesselheim, Jerry Avorn

Abstract

Strategic and legislative efforts to catalyse pharmaceutical innovation may be hampered by a lack of consensus over what characterizes an innovative drug. To help clarify this issue, we conducted an extensive survey on transformative drug development, involving ∼180 expert physicians based at 30 leading US academic medical centres, covering 15 medical specialties. In an iterative Delphi process, the survey participants narrowed a list of all new drugs approved in their fields in the past 25 years and reached consensus over those that they considered to be most transformative, which are presented in this article. Participants were also asked how various factors affected their opinion; they most often invoked the effectiveness and superiority of the drugs over existing alternatives when identifying transformative drug innovation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 40 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 3%
United Kingdom 3 2%
Colombia 1 <1%
Germany 1 <1%
Sri Lanka 1 <1%
Portugal 1 <1%
Greece 1 <1%
Spain 1 <1%
Unknown 114 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 39 31%
Other 20 16%
Student > Ph. D. Student 13 10%
Professor 12 9%
Student > Bachelor 10 8%
Other 27 21%
Unknown 6 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 27%
Medicine and Dentistry 28 22%
Chemistry 19 15%
Pharmacology, Toxicology and Pharmaceutical Science 9 7%
Biochemistry, Genetics and Molecular Biology 8 6%
Other 19 15%
Unknown 10 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 69. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2023.
All research outputs
#617,224
of 25,468,708 outputs
Outputs from Nature Reviews Drug Discovery
#277
of 3,667 outputs
Outputs of similar age
#4,371
of 208,942 outputs
Outputs of similar age from Nature Reviews Drug Discovery
#3
of 47 outputs
Altmetric has tracked 25,468,708 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,667 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.