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Safety and Immunogenicity Study of a 9-Valent Human Papillomavirus Vaccine Administered to 9-To-15 Year-Old Japanese Girls

Overview of attention for article published in Japanese Journal of Infectious Diseases, December 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 361)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

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125 tweeters
facebook
1 Facebook page

Citations

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5 Dimensions

Readers on

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12 Mendeley
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Title
Safety and Immunogenicity Study of a 9-Valent Human Papillomavirus Vaccine Administered to 9-To-15 Year-Old Japanese Girls
Published in
Japanese Journal of Infectious Diseases, December 2016
DOI 10.7883/yoken.jjid.2016.299
Pubmed ID
Authors

Iwata, Satoshi, Murata, Shinya, Han, Shi Rong, Wakana, Akira, Sawata, Miyuki, Tanaka, Yoshiyuki, Satoshi Iwata, Shinya Murata, Shi Rong Han, Akira Wakana, Miyuki Sawata, Yoshiyuki Tanaka

Abstract

A 9-valent human papillomavirus (HPV 6/11/16/18/31/33/45/52/58) virus-like particle (VLP) vaccine (9vHPV) has been proven highly efficacious in preventing anogenital disease related with vaccine HPV types in a pivotal Phase III study in women aged 16 to 26 years. We report here the results of an open-label phase III study conducted to bridge the findings in women age 16 to 26 years to Japanese girls aged 9 to 15 years. All subjects (n = 100) received a 3-dose regimen of 9vHPV vaccine at day 1, month 2 and month 6. Anti-HPV serologic assays were performed at day 1, month 7, month 12, month 24 and month 30. At month 7 (4 weeks after dose 3), 100% of subjects seroconverted for each vaccine HPV type. Increases in geometric mean titers of anti-HPV 6/11/16/18/31/33/45/52/58 in girls were similar to those in Japanese women aged 16 to 26 years in the pivotal phase III study. Persistence of anti-HPV responses was observed through 2 years after dose 3. In addition, administration of 9vHPV vaccine was generally well tolerated in Japanese girls.

Twitter Demographics

The data shown below were collected from the profiles of 125 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 33%
Student > Bachelor 3 25%
Student > Master 3 25%
Professor 1 8%
Student > Doctoral Student 1 8%
Other 0 0%
Readers by discipline Count As %
Medicine and Dentistry 4 33%
Agricultural and Biological Sciences 2 17%
Nursing and Health Professions 2 17%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Social Sciences 1 8%
Other 2 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 88. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2018.
All research outputs
#151,444
of 12,124,619 outputs
Outputs from Japanese Journal of Infectious Diseases
#1
of 361 outputs
Outputs of similar age
#7,988
of 328,188 outputs
Outputs of similar age from Japanese Journal of Infectious Diseases
#1
of 44 outputs
Altmetric has tracked 12,124,619 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 361 research outputs from this source. They receive a mean Attention Score of 1.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,188 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.