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Dengue virus serotype infection specifies the activation of the unfolded protein response

Overview of attention for article published in Virology Journal, September 2007
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Title
Dengue virus serotype infection specifies the activation of the unfolded protein response
Published in
Virology Journal, September 2007
DOI 10.1186/1743-422x-4-91
Pubmed ID
Authors

Indira Umareddy, Olivier Pluquet, Qing Yin Wang, Subhash G Vasudevan, Eric Chevet, Feng Gu

Abstract

Dengue and Dengue hemorrhagic fever have emerged as some of the most important mosquito-borne viral diseases in the tropics. The mechanisms of pathogenesis of Dengue remain elusive. Recently, virus-induced apoptosis mediated by the Unfolded Protein Response (UPR) has been hypothesised to represent a crucial pathogenic event in viral infection. In an attempt to evaluate the contribution of the UPR to virus replication, we have characterized each component of this signalling pathway following Dengue virus infection.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Brazil 2 <1%
India 2 <1%
Germany 1 <1%
Mexico 1 <1%
United Kingdom 1 <1%
Unknown 193 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 49 24%
Student > Master 30 15%
Researcher 29 14%
Student > Bachelor 22 11%
Student > Doctoral Student 12 6%
Other 33 16%
Unknown 28 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 72 35%
Biochemistry, Genetics and Molecular Biology 35 17%
Medicine and Dentistry 19 9%
Immunology and Microbiology 17 8%
Chemistry 14 7%
Other 12 6%
Unknown 34 17%