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1H, 13C, and 15N resonance assignments of SarA monomer from Staphylococcus aureus in complex with DNA

Overview of attention for article published in Biomolecular NMR Assignments, July 2023
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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Title
1H, 13C, and 15N resonance assignments of SarA monomer from Staphylococcus aureus in complex with DNA
Published in
Biomolecular NMR Assignments, July 2023
DOI 10.1007/s12104-023-10140-8
Pubmed ID
Authors

Dihong Fu, Bo Duan, Xianzhi Dong, Bin Xia

Abstract

SarA is a global transcription regulator in S. aureus which regulates the expression of over 120 genes related to quorum sensing, biofilm synthesis, drug resistance and many other important physiological processes during host infection. SarA can bind to the promoter region of agr and other target genes to activate or repress the transcription. The crystal structure of SarA uncovered a MarR protein-like conformation with two symmetrical winged helix domains, while its DNA binding mechanism is still unknown. We have constructed a monomeric DNA binding domain of SarA (SarAΔN19) for the study of the interaction between SarA and DNA with NMR spectroscopy. Here, we report the 1H, 13C and 15N NMR assignment of SarAΔN19/DNA complex which is the first step towards further structure and function analysis.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2023.
All research outputs
#15,236,690
of 24,626,543 outputs
Outputs from Biomolecular NMR Assignments
#88
of 284 outputs
Outputs of similar age
#163,948
of 347,191 outputs
Outputs of similar age from Biomolecular NMR Assignments
#2
of 5 outputs
Altmetric has tracked 24,626,543 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 284 research outputs from this source. They receive a mean Attention Score of 1.8. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 347,191 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.