| Title |
Causes, consequences, and perspectives in the variations of intestinal density of colonization of multidrug-resistant enterobacteria
|
|---|---|
| Published in |
Frontiers in Microbiology, January 2013
|
| DOI | 10.3389/fmicb.2013.00129 |
| Pubmed ID | |
| Authors |
Etienne Ruppé, Antoine Andremont |
| Abstract |
The intestinal microbiota is a complex environment that hosts 10(13) to 10(14) bacteria. Among these bacteria stand multidrug-resistant enterobacteria (MDRE), which intestinal densities can substantially vary, especially according to antibiotic exposure. The intestinal density of MDRE and their relative abundance (i.e., the proportion between the density of MDRE and the density of total enterobacteria) could play a major role in the infection process or patient-to-patient transmission. This review discusses the recent advances in understanding (i) what causes variations in the density or relative abundance of intestinal colonization, (ii) what are the clinical consequences of these variations, and (iii) what are the perspectives for maintaining these markers at low levels. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 22% |
| Canada | 1 | 11% |
| Switzerland | 1 | 11% |
| Unknown | 5 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 56% |
| Scientists | 3 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| France | 1 | 1% |
| Brazil | 1 | 1% |
| Denmark | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 90 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 18% |
| Researcher | 14 | 15% |
| Student > Ph. D. Student | 12 | 13% |
| Student > Bachelor | 7 | 7% |
| Student > Postgraduate | 6 | 6% |
| Other | 20 | 21% |
| Unknown | 19 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 29% |
| Agricultural and Biological Sciences | 14 | 15% |
| Immunology and Microbiology | 9 | 9% |
| Biochemistry, Genetics and Molecular Biology | 8 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 11 | 12% |
| Unknown | 22 | 23% |