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Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Overview of attention for book
Cover of 'Inflammation-Associated Depression: Evidence, Mechanisms and Implications'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 2 Evidence for Inflammation-Associated Depression
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    Chapter 5 Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism.
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    Chapter 6 Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches.
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    Chapter 7 Depression in Autoimmune Diseases.
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    Chapter 12 Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders.
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    Chapter 13 The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications
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    Chapter 14 Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms.
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    Chapter 19 Are Non-steroidal Anti-Inflammatory Drugs Clinically Suitable for the Treatment of Symptoms in Depression-Associated Inflammation?
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    Chapter 23 Mechanisms of Inflammation-Associated Depression: Immune Influences on Tryptophan and Phenylalanine Metabolisms.
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    Chapter 25 Stress-Induced Microglia Activation and Monocyte Trafficking to the Brain Underlie the Development of Anxiety and Depression.
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    Chapter 26 The Promise and Limitations of Anti-Inflammatory Agents for the Treatment of Major Depressive Disorder
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    Chapter 28 Inflammation-Associated Co-morbidity Between Depression and Cardiovascular Disease
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    Chapter 30 Brain Structures Implicated in Inflammation-Associated Depression
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    Chapter 31 Does Diet Matter? The Use of Polyunsaturated Fatty Acids (PUFAs) and Other Dietary Supplements in Inflammation-Associated Depression.
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    Chapter 37 Immune-to-Brain Communication Pathways in Inflammation-Associated Sickness and Depression
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    Chapter 40 Inflammation Effects on Brain Glutamate in Depression: Mechanistic Considerations and Treatment Implications.
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    Chapter 43 Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression.
Attention for Chapter 7: Depression in Autoimmune Diseases.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#28 of 382)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
3 news outlets
wikipedia
1 Wikipedia page

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
71 Mendeley
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Chapter title
Depression in Autoimmune Diseases.
Chapter number 7
Book title
Inflammation-Associated Depression: Evidence, Mechanisms and Implications
Published in
Current topics in behavioral neurosciences, May 2016
DOI 10.1007/7854_2016_7
Pubmed ID
Book ISBNs
978-3-31-951151-1, 978-3-31-951152-8
Authors

Christopher R. Pryce, Adriano Fontana, Pryce, Christopher R., Fontana, Adriano

Editors

Robert Dantzer, Lucile Capuron

Abstract

Up to 50% of patients with autoimmune diseases show an impairment of health-related quality of life and exhibit depression-like symptoms. The immune system not only leads to inflammation in affected organs, but also mediates behavior abnormalities including fatigue and depression-like symptoms. This review focuses on the different pathways involved in the communication of the immune system with the neuronal network and the body's timing system. The latter is built up by a hierarchically organized expression of clock genes. As discussed here, the activation of the immune system interferes with high amplitude expression of clock genes, an effect which may play a pivotal role in depression-like behavior in autoimmune diseases.

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 17%
Student > Ph. D. Student 9 13%
Researcher 8 11%
Student > Master 8 11%
Student > Doctoral Student 7 10%
Other 12 17%
Unknown 15 21%
Readers by discipline Count As %
Medicine and Dentistry 17 24%
Psychology 7 10%
Agricultural and Biological Sciences 6 8%
Neuroscience 6 8%
Nursing and Health Professions 4 6%
Other 9 13%
Unknown 22 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2021.
All research outputs
#904,483
of 17,838,103 outputs
Outputs from Current topics in behavioral neurosciences
#28
of 382 outputs
Outputs of similar age
#27,757
of 396,058 outputs
Outputs of similar age from Current topics in behavioral neurosciences
#5
of 36 outputs
Altmetric has tracked 17,838,103 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 382 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,058 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.