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Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Overview of attention for book
Cover of 'Inflammation-Associated Depression: Evidence, Mechanisms and Implications'

Table of Contents

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    Book Overview
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    Chapter 2 Evidence for Inflammation-Associated Depression
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    Chapter 5 Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism.
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    Chapter 6 Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches.
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    Chapter 7 Depression in Autoimmune Diseases.
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    Chapter 12 Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders.
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    Chapter 13 The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications
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    Chapter 14 Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms.
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    Chapter 19 Are Non-steroidal Anti-Inflammatory Drugs Clinically Suitable for the Treatment of Symptoms in Depression-Associated Inflammation?
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    Chapter 23 Mechanisms of Inflammation-Associated Depression: Immune Influences on Tryptophan and Phenylalanine Metabolisms.
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    Chapter 25 Stress-Induced Microglia Activation and Monocyte Trafficking to the Brain Underlie the Development of Anxiety and Depression.
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    Chapter 26 The Promise and Limitations of Anti-Inflammatory Agents for the Treatment of Major Depressive Disorder
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    Chapter 28 Inflammation-Associated Co-morbidity Between Depression and Cardiovascular Disease
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    Chapter 30 Brain Structures Implicated in Inflammation-Associated Depression
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    Chapter 31 Does Diet Matter? The Use of Polyunsaturated Fatty Acids (PUFAs) and Other Dietary Supplements in Inflammation-Associated Depression.
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    Chapter 37 Immune-to-Brain Communication Pathways in Inflammation-Associated Sickness and Depression
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    Chapter 40 Inflammation Effects on Brain Glutamate in Depression: Mechanistic Considerations and Treatment Implications.
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    Chapter 43 Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression.
Attention for Chapter 30: Brain Structures Implicated in Inflammation-Associated Depression
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Citations

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38 Dimensions

Readers on

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102 Mendeley
Summary X Dimensions citations
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Chapter title
Brain Structures Implicated in Inflammation-Associated Depression
Chapter number 30
Book title
Inflammation-Associated Depression: Evidence, Mechanisms and Implications
Published in
Current topics in behavioral neurosciences, June 2016
DOI 10.1007/7854_2016_30
Pubmed ID
27272069
Book ISBNs
978-3-31-951151-1, 978-3-31-951152-8
Authors

Harrison, Neil A, Neil A. Harrison, Harrison, Neil A.

Editors

Robert Dantzer, Lucile Capuron

Abstract

Systemic inflammation rapidly impairs mood, motivation, and cognition inducing a stereotyped cluster of symptoms collectively known as "sickness behaviors." When inflammation is severe or chronic, these behavioral changes can appear indistinguishable from major depressive disorder (MDD). Human and rodent neuroimaging combined with experimental inflammatory challenges has clarified the neural circuitry associated with many of the key features of inflammation-induced-sickness behavior, and in so doing revealed often-remarkable commonalities with circuit abnormalities observed in MDD. This review aims to provide the first synthesis of this work illustrating areas of convergence and divergence with the MDD literature as well as highlighting areas for future study.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 101 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 18%
Researcher 18 18%
Student > Master 11 11%
Student > Bachelor 8 8%
Student > Doctoral Student 8 8%
Other 12 12%
Unknown 27 26%
Readers by discipline Count As %
Neuroscience 21 21%
Medicine and Dentistry 17 17%
Psychology 16 16%
Agricultural and Biological Sciences 4 4%
Social Sciences 3 3%
Other 10 10%
Unknown 31 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2017.
All research outputs
#16,015,562
of 25,330,051 outputs
Outputs from Current topics in behavioral neurosciences
#317
of 526 outputs
Outputs of similar age
#201,954
of 349,286 outputs
Outputs of similar age from Current topics in behavioral neurosciences
#9
of 16 outputs
Altmetric has tracked 25,330,051 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 526 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.4. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 349,286 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.

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