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Inflammation-Associated Depression: Evidence, Mechanisms and Implications

Overview of attention for book
Cover of 'Inflammation-Associated Depression: Evidence, Mechanisms and Implications'

Table of Contents

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    Book Overview
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    Chapter 2 Evidence for Inflammation-Associated Depression
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    Chapter 5 Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism.
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    Chapter 6 Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches.
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    Chapter 7 Depression in Autoimmune Diseases.
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    Chapter 12 Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders.
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    Chapter 13 The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications
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    Chapter 14 Role of Inflammation in the Development of Neuropsychiatric Symptom Domains: Evidence and Mechanisms.
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    Chapter 19 Are Non-steroidal Anti-Inflammatory Drugs Clinically Suitable for the Treatment of Symptoms in Depression-Associated Inflammation?
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    Chapter 23 Mechanisms of Inflammation-Associated Depression: Immune Influences on Tryptophan and Phenylalanine Metabolisms.
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    Chapter 25 Stress-Induced Microglia Activation and Monocyte Trafficking to the Brain Underlie the Development of Anxiety and Depression.
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    Chapter 26 The Promise and Limitations of Anti-Inflammatory Agents for the Treatment of Major Depressive Disorder
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    Chapter 28 Inflammation-Associated Co-morbidity Between Depression and Cardiovascular Disease
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    Chapter 30 Brain Structures Implicated in Inflammation-Associated Depression
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    Chapter 31 Does Diet Matter? The Use of Polyunsaturated Fatty Acids (PUFAs) and Other Dietary Supplements in Inflammation-Associated Depression.
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    Chapter 37 Immune-to-Brain Communication Pathways in Inflammation-Associated Sickness and Depression
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    Chapter 40 Inflammation Effects on Brain Glutamate in Depression: Mechanistic Considerations and Treatment Implications.
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    Chapter 43 Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression.
Attention for Chapter 30: Brain Structures Implicated in Inflammation-Associated Depression
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Mentioned by

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Citations

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22 Dimensions

Readers on

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77 Mendeley
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Chapter title
Brain Structures Implicated in Inflammation-Associated Depression
Chapter number 30
Book title
Inflammation-Associated Depression: Evidence, Mechanisms and Implications
Published in
Current topics in behavioral neurosciences, June 2016
DOI 10.1007/7854_2016_30
Pubmed ID
Book ISBNs
978-3-31-951151-1, 978-3-31-951152-8
Authors

Harrison, Neil A, Neil A. Harrison

Editors

Robert Dantzer, Lucile Capuron

Abstract

Systemic inflammation rapidly impairs mood, motivation, and cognition inducing a stereotyped cluster of symptoms collectively known as "sickness behaviors." When inflammation is severe or chronic, these behavioral changes can appear indistinguishable from major depressive disorder (MDD). Human and rodent neuroimaging combined with experimental inflammatory challenges has clarified the neural circuitry associated with many of the key features of inflammation-induced-sickness behavior, and in so doing revealed often-remarkable commonalities with circuit abnormalities observed in MDD. This review aims to provide the first synthesis of this work illustrating areas of convergence and divergence with the MDD literature as well as highlighting areas for future study.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
France 1 1%
Unknown 75 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 21%
Researcher 15 19%
Student > Master 10 13%
Student > Bachelor 7 9%
Student > Doctoral Student 7 9%
Other 11 14%
Unknown 11 14%
Readers by discipline Count As %
Neuroscience 18 23%
Psychology 17 22%
Medicine and Dentistry 13 17%
Agricultural and Biological Sciences 4 5%
Social Sciences 2 3%
Other 7 9%
Unknown 16 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2017.
All research outputs
#9,407,668
of 16,022,651 outputs
Outputs from Current topics in behavioral neurosciences
#194
of 366 outputs
Outputs of similar age
#128,630
of 268,428 outputs
Outputs of similar age from Current topics in behavioral neurosciences
#7
of 14 outputs
Altmetric has tracked 16,022,651 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 366 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,428 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.