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PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN ESOPHAGEAL CARCINOMA

Overview of attention for article published in ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), September 2016
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Title
PROGNOSTIC FACTORS AND SURVIVAL ANALYSIS IN ESOPHAGEAL CARCINOMA
Published in
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), September 2016
DOI 10.1590/0102-6720201600030003
Pubmed ID
Authors

Francisco TUSTUMI, Cintia Mayumi Sakurai KIMURA, Flavio Roberto TAKEDA, Rodrigo Hideki UEMA, Rubens Antônio Aissar SALUM, Ulysses RIBEIRO-JUNIOR, Ivan CECCONELLO

Abstract

Despite recent advances in diagnosis and treatment, esophageal cancer still has high mortality. Prognostic factors associated with patient and with disease itself are multiple and poorly explored. Assess prognostic variables in esophageal cancer patients. Retrospective review of all patients with esophageal cancer in an oncology referral center. They were divided according to histological diagnosis (444 squamous cell carcinoma patients and 105 adenocarcinoma), and their demographic, pathological and clinical characteristics were analyzed and compared to clinical stage and overall survival. No difference was noted between squamous cell carcinoma and esophageal adenocarcinoma overall survival curves. Squamous cell carcinoma presented 22.8% survival after five years against 20.2% for adenocarcinoma. When considering only patients treated with curative intent resection, after five years squamous cell carcinoma survival rate was 56.6 and adenocarcinoma, 58%. In patients with squamous cell carcinoma, poor differentiation histology and tumor size were associated with worse oncology stage, but this was not evidenced in adenocarcinoma. Weight loss (kg), BMI variation (kg/m²) and percentage of weight loss are factors that predict worse stage at diagnosis in the squamous cell carcinoma. In adenocarcinoma, these findings were not statistically significant. Apesar dos avanços recentes nos métodos diagnósticos e tratamento, o câncer de esôfago mantém alta mortalidade. Fatores prognósticos associados ao paciente e ao câncer propriamente dito são pouco conhecidos. Investigar variáveis prognósticas no câncer esofágico. Pacientes diagnosticados entre 2009 e 2012 foram analisados e subdivididos de acordo com tipo histológico (444 carcinomas espinocelulares e 105 adenocarcinomas), e então características demográficas, anatomopatológicas e clínicas foram analisadas. Não houve diferença entre os dois tipos histológicos na sobrevida global. Carcinoma espinocelular apresentou sobrevida de 22,8% em 5 anos, contra 20,2% de adenocarcinoma. Quando considerado somente os tratados com operação com intenção curativa, sobrevida em cinco anos foi de 56,6% para espinocelular e 58% para adenocarcinoma. Para o subtipo espinocelular, tumores pouco diferenciados e extensão tumoral mostraram associação com pior estadiamento oncológico, o que não foi verificado para adenocarcinoma. Perda de peso, variação de IMC e porcentagem de perda de peso foram fatores associados ao pior estadiamento oncológico para espinocelular, o que não se confirmou para adenocarcinoma.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 20%
Student > Master 5 14%
Professor > Associate Professor 4 11%
Student > Ph. D. Student 2 6%
Other 2 6%
Other 4 11%
Unknown 11 31%
Readers by discipline Count As %
Medicine and Dentistry 15 43%
Engineering 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Mathematics 1 3%
Agricultural and Biological Sciences 1 3%
Other 3 9%
Unknown 12 34%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2017.
All research outputs
#17,415,668
of 21,548,131 outputs
Outputs from ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
#128
of 221 outputs
Outputs of similar age
#310,256
of 420,276 outputs
Outputs of similar age from ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
#3
of 3 outputs
Altmetric has tracked 21,548,131 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 221 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,276 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.