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Myeloid-Derived Suppressor Cells

Overview of attention for article published in Cancer Immunology Research, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
11 tweeters
patent
5 patents
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
987 Dimensions

Readers on

mendeley
789 Mendeley
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Title
Myeloid-Derived Suppressor Cells
Published in
Cancer Immunology Research, January 2017
DOI 10.1158/2326-6066.cir-16-0297
Pubmed ID
Authors

Dmitry I. Gabrilovich

Abstract

Myeloid cells developed evolutionarily as a major mechanism to protect the host. They evolved as a critical barrier against infections and are important contributors to tissue remodeling. However, in cancer, myeloid cells are largely converted to serve a new master-tumor cells. This process is epitomized by myeloid-derived suppressor cells (MDSC). These cells are closely related to neutrophils and monocytes. MDSCs are not present in the steady state of healthy individuals and appear in cancer and in pathologic conditions associated with chronic inflammation or stress. These cells have emerged as an important contributor to tumor progression. Ample evidence supports a key role for MDSCs in immune suppression in cancer, as well as their prominent role in tumor angiogenesis, drug resistance, and promotion of tumor metastases. MDSCs have a fascinating biology and are implicated in limiting the effects of cancer immunotherapy. Therefore, targeting these cells may represent an attractive therapeutic opportunity. Cancer Immunol Res; 5(1); 3-8. ©2016 AACR.

Twitter Demographics

The data shown below were collected from the profiles of 11 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 789 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 789 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 161 20%
Researcher 125 16%
Student > Bachelor 104 13%
Student > Master 86 11%
Student > Doctoral Student 50 6%
Other 76 10%
Unknown 187 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 151 19%
Immunology and Microbiology 140 18%
Medicine and Dentistry 116 15%
Agricultural and Biological Sciences 80 10%
Pharmacology, Toxicology and Pharmaceutical Science 33 4%
Other 57 7%
Unknown 212 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2022.
All research outputs
#876,353
of 22,557,175 outputs
Outputs from Cancer Immunology Research
#90
of 1,387 outputs
Outputs of similar age
#22,194
of 425,273 outputs
Outputs of similar age from Cancer Immunology Research
#2
of 19 outputs
Altmetric has tracked 22,557,175 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,387 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 425,273 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.