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Myeloid-Derived Suppressor Cells

Overview of attention for article published in Cancer Immunology Research, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
11 X users
patent
7 patents
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
1331 Dimensions

Readers on

mendeley
904 Mendeley
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Title
Myeloid-Derived Suppressor Cells
Published in
Cancer Immunology Research, January 2017
DOI 10.1158/2326-6066.cir-16-0297
Pubmed ID
Authors

Dmitry I. Gabrilovich

Abstract

Myeloid cells developed evolutionarily as a major mechanism to protect the host. They evolved as a critical barrier against infections and are important contributors to tissue remodeling. However, in cancer, myeloid cells are largely converted to serve a new master-tumor cells. This process is epitomized by myeloid-derived suppressor cells (MDSC). These cells are closely related to neutrophils and monocytes. MDSCs are not present in the steady state of healthy individuals and appear in cancer and in pathologic conditions associated with chronic inflammation or stress. These cells have emerged as an important contributor to tumor progression. Ample evidence supports a key role for MDSCs in immune suppression in cancer, as well as their prominent role in tumor angiogenesis, drug resistance, and promotion of tumor metastases. MDSCs have a fascinating biology and are implicated in limiting the effects of cancer immunotherapy. Therefore, targeting these cells may represent an attractive therapeutic opportunity. Cancer Immunol Res; 5(1); 3-8. ©2016 AACR.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 904 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 904 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 169 19%
Researcher 132 15%
Student > Bachelor 118 13%
Student > Master 91 10%
Student > Doctoral Student 56 6%
Other 82 9%
Unknown 256 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 167 18%
Immunology and Microbiology 150 17%
Medicine and Dentistry 127 14%
Agricultural and Biological Sciences 86 10%
Pharmacology, Toxicology and Pharmaceutical Science 33 4%
Other 61 7%
Unknown 280 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2024.
All research outputs
#1,060,562
of 25,591,967 outputs
Outputs from Cancer Immunology Research
#108
of 1,574 outputs
Outputs of similar age
#21,886
of 423,624 outputs
Outputs of similar age from Cancer Immunology Research
#3
of 19 outputs
Altmetric has tracked 25,591,967 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,574 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,624 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.