Title |
Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip
|
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Published in |
Nature Communications, August 2017
|
DOI | 10.1038/s41467-017-00266-4 |
Pubmed ID | |
Authors |
P. Kehayias, A. Jarmola, N. Mosavian, I. Fescenko, F. M. Benito, A. Laraoui, J. Smits, L. Bougas, D. Budker, A. Neumann, S. R. J. Brueck, V. M. Acosta |
Abstract |
Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform (1)H and (19)F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 10(12 19)F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.Nitrogen vacancy (NV) centres in diamond can be used for NMR spectroscopy, but increased sensitivity is needed to avoid long measurement times. Kehayias et al. present a nanostructured diamond grating with a high density of NV centres, enabling NMR spectroscopy of picoliter-volume solutions. |
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