Title |
The collateral circulation of the heart
|
---|---|
Published in |
BMC Medicine, June 2013
|
DOI | 10.1186/1741-7015-11-143 |
Pubmed ID | |
Authors |
Pascal Meier, Stephan H Schirmer, Alexandra J Lansky, Adam Timmis, Bertram Pitt, Christian Seiler |
Abstract |
The coronary arteries have been regarded as end arteries for decades. However, there are functionally relevant anastomotic vessels, known as collateral arteries, which interconnect epicardial coronary arteries. These vessels provide an alternative source of blood supply to the myocardium in cases of occlusive coronary artery disease. The relevance of these collateral arteries is a matter of ongoing debate, but increasing evidence indicates a relevant protective role in patients with coronary artery disease. The collateral circulation can be assessed by different methods; the gold standard involves intracoronary pressure measurements. While the first clinical trials to therapeutically induce growth of collateral arteries have been unavailing, recent pilot studies using external counterpulsation or growth factors such as granulocyte colony stimulating factor (G-CSF) have shown promising results. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 40% |
Egypt | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Members of the public | 1 | 20% |
Scientists | 1 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
Unknown | 140 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 23 | 16% |
Student > Bachelor | 22 | 16% |
Researcher | 14 | 10% |
Other | 11 | 8% |
Student > Postgraduate | 11 | 8% |
Other | 34 | 24% |
Unknown | 26 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 61 | 43% |
Engineering | 14 | 10% |
Agricultural and Biological Sciences | 8 | 6% |
Unspecified | 6 | 4% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Other | 10 | 7% |
Unknown | 36 | 26% |