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Potential of patient-reported outcomes as nonprimary endpoints in clinical trials

Overview of attention for article published in Health and Quality of Life Outcomes, May 2013
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2 X users

Citations

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39 Dimensions

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58 Mendeley
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Title
Potential of patient-reported outcomes as nonprimary endpoints in clinical trials
Published in
Health and Quality of Life Outcomes, May 2013
DOI 10.1186/1477-7525-11-83
Pubmed ID
Authors

Ari Gnanasakthy, Sandra Lewis, Marci Clark, Margaret Mordin, Carla DeMuro

Abstract

The purpose of this research was to fully explore the impact of endpoint type (primary vs. nonprimary) on decisions related to patient-reported outcome (PRO) labeling claims supported by PRO measures and to determine if nonprimary PRO endpoints are being fully optimized.This review examines the use of PROs as both primary and nonprimary endpoints in support of demonstration of treatment benefit of new molecular entities (NMEs) and biologic license applications (BLAs) in the United States in the years 2000 to 2012.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Other 10 17%
Student > Master 10 17%
Student > Ph. D. Student 8 14%
Researcher 7 12%
Professor > Associate Professor 5 9%
Other 13 22%
Unknown 5 9%
Readers by discipline Count As %
Medicine and Dentistry 23 40%
Nursing and Health Professions 6 10%
Psychology 4 7%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Social Sciences 4 7%
Other 7 12%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2014.
All research outputs
#15,517,992
of 25,374,647 outputs
Outputs from Health and Quality of Life Outcomes
#1,210
of 2,297 outputs
Outputs of similar age
#116,149
of 207,021 outputs
Outputs of similar age from Health and Quality of Life Outcomes
#17
of 34 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,297 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,021 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.