↓ Skip to main content

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Overview of attention for article published in Nature Genetics, June 2013
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Citations

dimensions_citation
706 Dimensions

Readers on

mendeley
414 Mendeley
citeulike
3 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Published in
Nature Genetics, June 2013
DOI 10.1038/ng.2667
Pubmed ID
Abstract

Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting primarily the spine and pelvis. In addition to HLA-B*27 alleles, 12 loci have previously been identified that are associated with ankylosing spondylitis in populations of European ancestry, and 2 associated loci have been identified in Asians. In this study, we used the Illumina Immunochip microarray to perform a case-control association study involving 10,619 individuals with ankylosing spondylitis (cases) and 15,145 controls. We identified 13 new risk loci and 12 additional ankylosing spondylitis-associated haplotypes at 11 loci. Two ankylosing spondylitis-associated regions have now been identified encoding four aminopeptidases that are involved in peptide processing before major histocompatibility complex (MHC) class I presentation. Protective variants at two of these loci are associated both with reduced aminopeptidase function and with MHC class I cell surface expression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 414 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
United Kingdom 2 <1%
Colombia 1 <1%
Germany 1 <1%
Finland 1 <1%
Portugal 1 <1%
China 1 <1%
Turkey 1 <1%
Unknown 403 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 74 18%
Student > Ph. D. Student 73 18%
Student > Master 42 10%
Student > Bachelor 42 10%
Student > Doctoral Student 23 6%
Other 75 18%
Unknown 85 21%
Readers by discipline Count As %
Medicine and Dentistry 95 23%
Agricultural and Biological Sciences 83 20%
Biochemistry, Genetics and Molecular Biology 70 17%
Immunology and Microbiology 24 6%
Computer Science 7 2%
Other 34 8%
Unknown 101 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 35. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2024.
All research outputs
#1,172,456
of 26,017,215 outputs
Outputs from Nature Genetics
#1,920
of 7,655 outputs
Outputs of similar age
#9,445
of 214,173 outputs
Outputs of similar age from Nature Genetics
#28
of 70 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,655 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.8. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 214,173 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.