Title |
Intracavernous administration of bone marrow mononuclear cells: a new method of treating erectile dysfunction?
|
---|---|
Published in |
Journal of Translational Medicine, June 2013
|
DOI | 10.1186/1479-5876-11-139 |
Pubmed ID | |
Authors |
Thomas E Ichim, Timothy Warbington, Octav Cristea, Joseph L Chin, Amit N Patel |
Abstract |
While PDE5 inhibitors have revolutionized treatment of ED, approximately 30% of patients are non-responsive. A significant cause of this is vascular and smooth muscle dysfunction, as well as nerve atrophy. Autologous administration of bone marrow mononuclear cells (BMMC) has been performed in over 2000 cardiac patients without adverse effects, for stimulation of angiogenesis/regeneration. Despite its ease of access, and dependence on effective vasculature for function, comparatively little has been perform in terms of BMMC therapy for ED. Here we outline the rationale for use of autologous BMMC in patients with ED, as well as provide early safety data on the first use of this procedure clinically. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 20 | 53% |
Canada | 2 | 5% |
Germany | 1 | 3% |
Unknown | 15 | 39% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 34 | 89% |
Practitioners (doctors, other healthcare professionals) | 2 | 5% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Unknown | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 15% |
Other | 5 | 10% |
Student > Ph. D. Student | 4 | 8% |
Student > Master | 3 | 6% |
Professor > Associate Professor | 3 | 6% |
Other | 4 | 8% |
Unknown | 22 | 46% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 27% |
Engineering | 3 | 6% |
Nursing and Health Professions | 2 | 4% |
Psychology | 2 | 4% |
Sports and Recreations | 2 | 4% |
Other | 4 | 8% |
Unknown | 22 | 46% |