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Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support ‘end game’ interventions

Overview of attention for article published in Infectious Diseases of Poverty, January 2017
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Title
Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support ‘end game’ interventions
Published in
Infectious Diseases of Poverty, January 2017
DOI 10.1186/s40249-016-0215-9
Pubmed ID
Authors

J. Russell Stothard, Suzy J. Campbell, Mike Y. Osei-Atweneboana, Timothy Durant, Michelle C. Stanton, Nana-Kwadwo Biritwum, David Rollinson, Dieudonné R. Eloundou Ombede, Louis-Albert Tchuem-Tchuenté

Abstract

Schistosomiasis is a waterborne parasitic disease in sub-Saharan Africa, particularly common in rural populations living in impoverished conditions. With the scale-up of preventive chemotherapy, national campaigns will transition from morbidity- to transmission-focused interventions thus formal investigation of actual or expected declines in environmental transmission is needed as 'end game' scenarios arise. Surprisingly, there are no international or national guidelines to do so in sub-Saharan Africa. Our article therefore provides an introduction to key practicalities and pitfalls in the development of an appropriate environmental surveillance framework. In this context, we discuss how strategies need to be adapted and tailored to the local level to better guide and support future interventions through this transition. As detection of egg-patent infection in people becomes rare, careful sampling of schistosome larvae in freshwater and in aquatic snails with robust species-specific DNA assays will be required. Appropriate metrics, derived from observed prevalence(s) as compared with predetermined thresholds, could each provide a clearer insight into contamination- and exposure-related dynamics. Application could be twofold, first to certify areas currently free from schistosomiasis transmission or second to red-flag recalcitrant locations where extra effort or alternative interventions are needed.

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Mendeley readers

The data shown below were compiled from readership statistics for 213 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 212 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 37 17%
Student > Ph. D. Student 28 13%
Researcher 27 13%
Student > Bachelor 18 8%
Student > Postgraduate 11 5%
Other 35 16%
Unknown 57 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 16%
Medicine and Dentistry 34 16%
Biochemistry, Genetics and Molecular Biology 16 8%
Environmental Science 16 8%
Nursing and Health Professions 11 5%
Other 40 19%
Unknown 62 29%