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Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse

Overview of attention for article published in Cancer Nanotechnology, July 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#11 of 218)
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user

Citations

dimensions_citation
131 Dimensions

Readers on

mendeley
141 Mendeley
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Title
Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse
Published in
Cancer Nanotechnology, July 2012
DOI 10.1007/s12645-012-0029-9
Pubmed ID
Authors

Mi-Ran Choi, Rizia Bardhan, Katie J. Stanton-Maxey, Sunil Badve, Harikrishna Nakshatri, Keith M. Stantz, Ning Cao, Naomi J. Halas, Susan E. Clare

Abstract

As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood-brain barrier (BBB) represents a major challenge to the delivery of therapeutics to the brain. Macrophages originating from circulating monocytes are able to infiltrate brain metastases while the BBB is intact. Here, we show that this ability can be exploited to deliver both diagnostic and therapeutic nanoparticles specifically to experimental brain metastases of breast cancer.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Egypt 2 1%
Canada 1 <1%
United States 1 <1%
Unknown 137 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 29%
Researcher 21 15%
Student > Bachelor 14 10%
Student > Master 10 7%
Student > Doctoral Student 7 5%
Other 21 15%
Unknown 27 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 19%
Chemistry 18 13%
Engineering 14 10%
Medicine and Dentistry 13 9%
Pharmacology, Toxicology and Pharmaceutical Science 12 9%
Other 23 16%
Unknown 34 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2023.
All research outputs
#3,253,957
of 23,940,484 outputs
Outputs from Cancer Nanotechnology
#11
of 218 outputs
Outputs of similar age
#20,618
of 166,056 outputs
Outputs of similar age from Cancer Nanotechnology
#1
of 2 outputs
Altmetric has tracked 23,940,484 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 218 research outputs from this source. They receive a mean Attention Score of 2.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,056 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them