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Auto-titrating continuous positive airway pressure treatment for obstructive sleep apnoea after acute quadriplegia (COSAQ): study protocol for a randomized controlled trial

Overview of attention for article published in Trials, June 2013
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Title
Auto-titrating continuous positive airway pressure treatment for obstructive sleep apnoea after acute quadriplegia (COSAQ): study protocol for a randomized controlled trial
Published in
Trials, June 2013
DOI 10.1186/1745-6215-14-181
Pubmed ID
Authors

David J Berlowitz, Najib Ayas, Maree Barnes, Douglas J Brown, Peter A Cistulli, Tim Geraghty, Alison Graham, Gerard A Kennedy, Bonsan Bonne Lee, Meg Morris, Fergal O’Donoghue, Peter D Rochford, Jack Ross, Balraj Singhal, Jo Spong, Brooke Wadsworth, Robert J Pierce

Abstract

Quadriplegia is a severe, catastrophic injury that predominantly affects people early in life, resulting in lifelong physical disability. Obstructive sleep apnoea is a direct consequence of quadriplegia and is associated with neurocognitive deficits, sleepiness and reduced quality of life. The usual treatment for sleep apnoea is nasal continuous positive airway pressure (CPAP); however, this is poorly tolerated in quadriplegia. To encourage patients to use this therapy, we have to demonstrate that the benefits outweigh the inconvenience. We therefore propose a prospective, multinational randomized controlled trial of three months of CPAP for obstructive sleep apnoea after acute quadriplegia.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Brazil 1 1%
Unknown 91 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 19%
Student > Bachelor 16 17%
Researcher 7 8%
Student > Doctoral Student 6 6%
Student > Ph. D. Student 6 6%
Other 19 20%
Unknown 21 23%
Readers by discipline Count As %
Medicine and Dentistry 34 37%
Nursing and Health Professions 17 18%
Psychology 6 6%
Social Sciences 5 5%
Economics, Econometrics and Finance 2 2%
Other 7 8%
Unknown 22 24%