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Efetividade da suplementação de sulfato ferroso na prevenção da anemia em crianças: revisão sistemática da literatura e metanálise

Overview of attention for article published in Cadernos de Saúde Pública, September 2013
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Title
Efetividade da suplementação de sulfato ferroso na prevenção da anemia em crianças: revisão sistemática da literatura e metanálise
Published in
Cadernos de Saúde Pública, September 2013
DOI 10.1590/0102-311x00152312
Pubmed ID
Authors

Francieli Cembranel, Camila Dallazen, David Alejandro González-Chica

Abstract

This was a systematic review and meta-analysis of studies evaluating the effectiveness of ferrous sulfate supplementation in the prevention of anemia in children under five. The database search included PubMed, Scopus, LILACS, and SciELO. Articles published between 1980 and 2011 in Spanish, English, or Portuguese were included, using the keywords child, preschool, infant, anemia, prevention, and iron supplementation. The authors selected 13 studies, which showed that regardless of dose and duration of supplementation, daily regimen was more consistently related to improvement in hemoglobin levels (pooled effect 0.56mg/dL, 95%CI: 0.31; 0.81, p < 0.001) as compared to weekly intervention (pooled effect 0.28mg/dL, 95%CI: -0.22; 0.78, p = 0.273). Iron supplementation was not associated with decreased prevalence of anemia, even with daily doses, and administration with other micronutrients did not bring additional benefits compared to the exclusive administration of iron supplement. Daily supplementation of ferrous sulfate was more effective than weekly doses in improving hemoglobin levels.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 5%
Peru 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 43%
Student > Postgraduate 4 10%
Student > Doctoral Student 3 7%
Professor 3 7%
Student > Master 2 5%
Other 4 10%
Unknown 8 19%
Readers by discipline Count As %
Nursing and Health Professions 8 19%
Medicine and Dentistry 6 14%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Biochemistry, Genetics and Molecular Biology 3 7%
Agricultural and Biological Sciences 3 7%
Other 7 17%
Unknown 12 29%