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Birth Weight in Different Etiologies of Disorders of Sex Development

Overview of attention for article published in The Journal of Clinical Endocrinology & Metabolism, January 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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6 tweeters
facebook
1 Facebook page

Citations

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3 Dimensions

Readers on

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12 Mendeley
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Title
Birth Weight in Different Etiologies of Disorders of Sex Development
Published in
The Journal of Clinical Endocrinology & Metabolism, January 2017
DOI 10.1210/jc.2016-3460
Pubmed ID
Authors

Poyrazoglu, S, Darendeliler, F, Ahmed, SF, Hughes, IA, Bryce, J, Jiang, J, Rodie, M, Hiort, O, Hannema, SE, Bertelloni, S, Lisa, L, Guran, T, Cools, M, Desloovere, A, Claahsen-van der Grinten, HL, Nordenstrom, A, Holterhus, PM, Kohler, B, Niedziela, M, Krone, N, Poyrazoglu, Sukran, Darendeliler, Feyza, Ahmed, S. Faisal, Hughes, Ieuan, Bryce, Jillian, Jiang, Jipu, Rodie, Martina, Hiort, Olaf, Hannema, Sabine E., Bertelloni, Silvano, Lisa, Lidka, Guran, Tulay, Cools, Martine, Desloovere, An, Claahsen-van der Grinten, Hedi L., Nordenstrom, Anna, Holterhus, Paul-Martin, Kohler, Birgit, Niedziela, Marek, Krone, Nils, Ahmed, S Faisal, Hannema, Sabine E, Claahsen-van der Grinten, Hedi L

Abstract

It is well established that boys are heavier than girls at birth. Although the cause of birth weight (BW) difference is unknown, it has been proposed that it could be generated from prenatal androgen action. The aim of the current study was to determine the BW of children with disorders of sex development (DSD) of different etiologies and to evaluate the effects of androgen action on BW. Data regarding diagnosis, BW, gestational age, karyotype, and concomitant conditions were collected from the International Disorders of Sex Development (I-DSD) Registry (www.i-dsd). BW standard deviation score was calculated according to gestational age. Cases were evaluated according to disorder classification in I-DSD (i.e., disorders of gonadal development, androgen excess, androgen synthesis, androgen action, nonspecific disorder of undermasculinization groups, and Leydig cell defect). A total of 533 cases were available; 400 (75%) cases were 46,XY, and 133 (25%) cases were 46,XX. Eighty cases (15%) were born small for gestational age (SGA). Frequency of SGA was higher in the 46,XY group (17.8%) than in the 46,XX (6.7%) group (P = 0.001). Mean BW standard deviation scores of cases with androgen excess and androgen deficiency [in disorders of gonadal development, androgen synthesis, and Leydig cell defect groups and androgen receptor gene (AR) mutation-positive cases in disorders of androgen action groups] were similar to normal children with the same karyotype. SGA birth frequency was higher in the AR mutation-negative cases in disorders of androgen action group and in the nonspecific disorders of the undermasculinization group. BW dimorphism is unlikely to be explained by fetal androgen action per se. 46,XY DSDs due to nonspecific disorders of undermasculinization are more frequently associated with fetal growth restriction, SGA, and concomitant conditions.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 17%
Student > Bachelor 2 17%
Researcher 2 17%
Student > Ph. D. Student 2 17%
Other 1 8%
Other 3 25%
Readers by discipline Count As %
Medicine and Dentistry 5 42%
Unspecified 3 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 8%
Agricultural and Biological Sciences 1 8%
Psychology 1 8%
Other 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2017.
All research outputs
#2,345,860
of 9,732,024 outputs
Outputs from The Journal of Clinical Endocrinology & Metabolism
#2,010
of 7,540 outputs
Outputs of similar age
#96,592
of 316,755 outputs
Outputs of similar age from The Journal of Clinical Endocrinology & Metabolism
#16
of 28 outputs
Altmetric has tracked 9,732,024 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,540 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,755 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.