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Management of upper airway edema caused by hereditary angioedema

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, July 2010
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Title
Management of upper airway edema caused by hereditary angioedema
Published in
Allergy, Asthma & Clinical Immunology, July 2010
DOI 10.1186/1710-1492-6-19
Pubmed ID
Authors

Henriette Farkas

Abstract

Hereditary angioedema is a rare disorder with a genetic background involving mutations in the genes encoding C1-INH and of factor XII. Its etiology is unknown in a proportion of cases. Recurrent edema formation may involve the subcutis and the submucosa - the latter can produce obstruction in the upper airways and thereby lead to life-threatening asphyxia. This is the reason for the high, 30-to 50-per-cent mortality of undiagnosed or improperly managed cases. Airway obstruction can be prevented through early diagnosis, meaningful patient information, timely recognition of initial symptoms, state-of-the-art emergency therapy, and close monitoring of the patient. Prophylaxis can substantially mitigate the risk of upper airway edema and also improve the patients' quality of life. Notwithstanding the foregoing, any form of upper airway edema should be regarded as a potentially life-threatening condition. None of the currently available prophylactic modalities is capable of preventing UAE with absolute certainty.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Turkey 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 18%
Other 4 9%
Student > Ph. D. Student 4 9%
Student > Master 4 9%
Student > Postgraduate 3 7%
Other 8 18%
Unknown 14 31%
Readers by discipline Count As %
Medicine and Dentistry 23 51%
Immunology and Microbiology 3 7%
Agricultural and Biological Sciences 3 7%
Biochemistry, Genetics and Molecular Biology 1 2%
Nursing and Health Professions 1 2%
Other 1 2%
Unknown 13 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2013.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#884
of 924 outputs
Outputs of similar age
#98,599
of 103,502 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#9
of 10 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,502 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one.