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X Demographics
Mendeley readers
Attention Score in Context
| Title |
TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease
|
|---|---|
| Published in |
Molecular Neurodegeneration, June 2013
|
| DOI | 10.1186/1750-1326-8-19 |
| Pubmed ID | |
| Authors |
Sruti Rayaprolu, Bianca Mullen, Matt Baker, Timothy Lynch, Elizabeth Finger, William W Seeley, Kimmo J Hatanpaa, Catherine Lomen-Hoerth, Andrew Kertesz, Eileen H Bigio, Carol Lippa, Keith A Josephs, David S Knopman, Charles L White, Richard Caselli, Ian R Mackenzie, Bruce L Miller, Magdalena Boczarska-Jedynak, Grzegorz Opala, Anna Krygowska-Wajs, Maria Barcikowska, Steven G Younkin, Ronald C Petersen, Nilüfer Ertekin-Taner, Ryan J Uitti, James F Meschia, Kevin B Boylan, Bradley F Boeve, Neill R Graff-Radford, Zbigniew K Wszolek, Dennis W Dickson, Rosa Rademakers, Owen A Ross |
| Abstract |
A rare variant in the Triggering Receptor Expressed on Myeloid cells 2 (TREM2) gene has been reported to be a genetic risk factor for Alzheimer's disease by two independent groups (Odds ratio between 2.9-4.5). Given the key role of TREM2 in the effective phagocytosis of apoptotic neuronal cells by microglia, we hypothesized that dysfunction of TREM2 may play a more generalized role in neurodegeneration. With this in mind we set out to assess the genetic association of the Alzheimer's disease-related risk variant in TREM2 (rs75932628, p.R47H) with other related neurodegenerative disorders. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 50% |
| United Kingdom | 1 | 17% |
| Spain | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 286 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 1% |
| Colombia | 2 | <1% |
| Netherlands | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Spain | 1 | <1% |
| Greece | 1 | <1% |
| United States | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 274 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 53 | 19% |
| Researcher | 52 | 18% |
| Student > Bachelor | 34 | 12% |
| Student > Master | 31 | 11% |
| Student > Doctoral Student | 17 | 6% |
| Other | 46 | 16% |
| Unknown | 53 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 66 | 23% |
| Agricultural and Biological Sciences | 44 | 15% |
| Biochemistry, Genetics and Molecular Biology | 37 | 13% |
| Medicine and Dentistry | 33 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 2% |
| Other | 30 | 10% |
| Unknown | 69 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2021.
All research outputs
#1,859,076
of 22,745,803 outputs
Outputs from Molecular Neurodegeneration
#174
of 845 outputs
Outputs of similar age
#16,863
of 196,882 outputs
Outputs of similar age from Molecular Neurodegeneration
#1
of 9 outputs
Altmetric has tracked 22,745,803 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 845 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,882 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them