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12/23 - $ARDX RDX8490 (TGR5 Agonist confined to GI tract for safety) acts like GLP-1 agonists Ozempic (semaglutide), Victoza (liraglutide) Wegovy, and Saxenda.
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“TGR5 has a high expression in the intestine, and its activation in enterocytes stimulates the secretion of the incretin GLP-1, promoting glucose-dependent insulin secretion.” https://t.co/nQXsELeY2E
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RT @TonyFauci2: “In L cells of the intestine, TGR5 stimulates the secretion of GLP-1 and the anorectic hormone peptide YY” https://t.co/nQX…
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“In L cells of the intestine, TGR5 stimulates the secretion of GLP-1 and the anorectic hormone peptide YY” https://t.co/nQXsELeY2E $ARDX RXD009 & RDX8490 TGR5 agonists for obesity.