Title |
Application of the Crystalline Sponge Method to Revise the Structure of the Phenalenone Fuliginone
|
---|---|
Published in |
Molecules, January 2017
|
DOI | 10.3390/molecules22020211 |
Pubmed ID | |
Authors |
Robert Brkljača, Bernd Schneider, William Hidalgo, Felipe Otálvaro, Felipe Ospina, Shoukou Lee, Manabu Hoshino, Makoto Fujita, Sylvia Urban |
Abstract |
The structure of fuliginone was revised from a phenyl substituted phenalenone to a hydroxyl substituted phenalenone as a result of its re-purification via HPLC with subsequent NMR analysis together with an independent synthesis and analysis of the crystal structure, which was secured via the crystalline sponge method. On-flow High Performance Liquid Chromatography coupled to Nuclear Magnetic Resonance spectroscopy (HPLC-NMR) was employed to confirm the presence of the natural product in the plant extract and to monitor for any possible degradation or conversion of the compound. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 33% |
United States | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 22% |
Student > Master | 9 | 18% |
Researcher | 6 | 12% |
Student > Bachelor | 3 | 6% |
Student > Doctoral Student | 2 | 4% |
Other | 5 | 10% |
Unknown | 14 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 31 | 62% |
Agricultural and Biological Sciences | 3 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Nursing and Health Professions | 1 | 2% |
Unknown | 13 | 26% |