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SDF-1–CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1–SLIT2 interactions in mice

Overview of attention for article published in Diabetologia, June 2013
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Title
SDF-1–CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1–SLIT2 interactions in mice
Published in
Diabetologia, June 2013
DOI 10.1007/s00125-013-2978-x
Pubmed ID
Authors

John D. Glawe, Eleni M. Mijalis, William C. Davis, Shayne C. Barlow, Neslihan Gungor, Robert McVie, Christopher G. Kevil

Abstract

We had previously reported that stromal cell-derived factor 1 (SDF-1) mediates chemorepulsion of diabetogenic T cell adhesion to islet microvascular endothelium through unknown mechanisms in NOD mice. Here we report that SDF-1-mediated chemorepulsion occurs through slit homologue (SLIT)2-roundabout, axon guidance receptor, homologue 1 (Drosophila) (ROBO1) interactions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 30%
Researcher 4 20%
Other 3 15%
Lecturer > Senior Lecturer 1 5%
Student > Doctoral Student 1 5%
Other 4 20%
Unknown 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 30%
Medicine and Dentistry 4 20%
Biochemistry, Genetics and Molecular Biology 3 15%
Environmental Science 1 5%
Nursing and Health Professions 1 5%
Other 3 15%
Unknown 2 10%