Title |
Transcriptome response to alkane biofuels in Saccharomyces cerevisiae: identification of efflux pumps involved in alkane tolerance
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Published in |
Biotechnology for Biofuels and Bioproducts, July 2013
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DOI | 10.1186/1754-6834-6-95 |
Pubmed ID | |
Authors |
Hua Ling, Binbin Chen, Aram Kang, Jong-Min Lee, Matthew Wook Chang |
Abstract |
Hydrocarbon alkanes have been recently considered as important next-generation biofuels because microbial production of alkane biofuels was demonstrated. However, the toxicity of alkanes to microbial hosts can possibly be a bottleneck for high productivity of alkane biofuels. To tackle this toxicity issue, it is essential to understand molecular mechanisms of interactions between alkanes and microbial hosts, and to harness these mechanisms to develop microbial host strains with improved tolerance against alkanes. In this study, we aimed to improve the tolerance of Saccharomyces cerevisiae, a model eukaryotic host of industrial significance, to alkane biofuels by exploiting cellular mechanisms underlying alkane response. |
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Geographical breakdown
Country | Count | As % |
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Indonesia | 1 | <1% |
United States | 1 | <1% |
India | 1 | <1% |
Sweden | 1 | <1% |
Unknown | 99 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 24 | 23% |
Student > Ph. D. Student | 23 | 22% |
Student > Master | 16 | 16% |
Student > Bachelor | 13 | 13% |
Student > Doctoral Student | 5 | 5% |
Other | 11 | 11% |
Unknown | 11 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 46 | 45% |
Biochemistry, Genetics and Molecular Biology | 24 | 23% |
Engineering | 9 | 9% |
Chemical Engineering | 3 | 3% |
Chemistry | 2 | 2% |
Other | 6 | 6% |
Unknown | 13 | 13% |