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X Demographics
Mendeley readers
| Title |
Antimutagenic and antirecombinagenic activities of noni fruit juice in somatic cells of Drosophila melanogaster
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, June 2013
|
| DOI | 10.1590/s0001-37652013000200008 |
| Pubmed ID | |
| Authors |
LEONARDO P. FRANCHI, NILZA N. GUIMARÃES, LAISE R. DE ANDRADE, HELOÍSA H.R. DE ANDRADE, MAURÍCIO LEHMANN, RAFAEL R. DIHL, KÊNYA S. CUNHA |
| Abstract |
Noni, a Hawaiian name for the fruit of Morinda citrifolia L., is a traditional medicinal plant from Polynesia widely used for the treatment of many diseases including arthritis, diabetes, asthma, hypertension and cancer. Here, a commercial noni juice (TNJ) was evaluated for its protective activities against the lesions induced by mitomycin C (MMC) and doxorrubicin (DXR) using the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. Three-day-old larvae, trans-heterozygous for two genetic markers (mwh and flr3 ), were co-treated with TNJ plus MMC or DXR. We have observed a reduction in genotoxic effects of MMC and DXR caused by the juice. TNJ provoked a marked decrease in all kinds of MMC- and DXR-induced mutant spots, mainly due to its antirecombinagenic activity. The TNJ protective effects were concentration-dependent, indicating a dose-response correlation, that can be attributed to a powerful antioxidant and/or free radical scavenger ability of TNJ. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 33% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 50 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 18% |
| Student > Bachelor | 8 | 16% |
| Professor | 4 | 8% |
| Student > Postgraduate | 3 | 6% |
| Student > Doctoral Student | 2 | 4% |
| Other | 8 | 16% |
| Unknown | 16 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 16% |
| Agricultural and Biological Sciences | 6 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Chemistry | 3 | 6% |
| Medicine and Dentistry | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 18 | 36% |