Title |
Novel transcriptional profile in wrist muscles from cerebral palsy patients
|
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Published in |
BMC Medical Genomics, July 2009
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DOI | 10.1186/1755-8794-2-44 |
Pubmed ID | |
Authors |
Lucas R Smith, Eva Pontén, Yvette Hedström, Samuel R Ward, Henry G Chambers, Shankar Subramaniam, Richard L Lieber |
Abstract |
Cerebral palsy (CP) is an upper motor neuron disease that results in a progressive movement disorder. Secondary to the neurological insult, muscles from CP patients often become spastic. Spastic muscle is characterized by an increased resistance to stretch, but often develops the further complication of contracture which represents a prominent disability in children with CP. This study's purpose is to characterize alterations of spastic muscle on the transcriptional level. Increased knowledge of spastic muscle may lead to novel therapies to improve the quality of life for children with CP. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | 1% |
Taiwan | 1 | 1% |
Unknown | 91 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 19% |
Student > Ph. D. Student | 13 | 14% |
Student > Master | 11 | 12% |
Student > Bachelor | 10 | 11% |
Professor | 8 | 9% |
Other | 20 | 22% |
Unknown | 13 | 14% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 14 | 15% |
Engineering | 7 | 8% |
Social Sciences | 6 | 6% |
Nursing and Health Professions | 4 | 4% |
Other | 16 | 17% |
Unknown | 22 | 24% |