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Novel metabolic and physiological functions of branched chain amino acids: a review

Overview of attention for article published in Journal of Animal Science and Biotechnology, January 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 917)
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
1 news outlet
twitter
6 X users
patent
2 patents
facebook
1 Facebook page
video
1 YouTube creator

Citations

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407 Dimensions

Readers on

mendeley
573 Mendeley
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Title
Novel metabolic and physiological functions of branched chain amino acids: a review
Published in
Journal of Animal Science and Biotechnology, January 2017
DOI 10.1186/s40104-016-0139-z
Pubmed ID
Authors

Shihai Zhang, Xiangfang Zeng, Man Ren, Xiangbing Mao, Shiyan Qiao

Abstract

It is widely known that branched chain amino acids (BCAA) are not only elementary components for building muscle tissue but also participate in increasing protein synthesis in animals and humans. BCAA (isoleucine, leucine and valine) regulate many key signaling pathways, the most classic of which is the activation of the mTOR signaling pathway. This signaling pathway connects many diverse physiological and metabolic roles. Recent years have witnessed many striking developments in determining the novel functions of BCAA including: (1) Insufficient or excessive levels of BCAA in the diet enhances lipolysis. (2) BCAA, especially isoleucine, play a major role in enhancing glucose consumption and utilization by up-regulating intestinal and muscular glucose transporters. (3) Supplementation of leucine in the diet enhances meat quality in finishing pigs. (4) BCAA are beneficial for mammary health, milk quality and embryo growth. (5) BCAA enhance intestinal development, intestinal amino acid transportation and mucin production. (6) BCAA participate in up-regulating innate and adaptive immune responses. In addition, abnormally elevated BCAA levels in the blood (decreased BCAA catabolism) are a good biomarker for the early detection of obesity, diabetes and other metabolic diseases. This review will provide some insights into these novel metabolic and physiological functions of BCAA.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 573 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
Unknown 572 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 96 17%
Student > Bachelor 87 15%
Student > Master 76 13%
Researcher 49 9%
Student > Doctoral Student 24 4%
Other 68 12%
Unknown 173 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 111 19%
Biochemistry, Genetics and Molecular Biology 91 16%
Medicine and Dentistry 43 8%
Chemistry 26 5%
Sports and Recreations 18 3%
Other 94 16%
Unknown 190 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 March 2023.
All research outputs
#2,343,578
of 25,483,400 outputs
Outputs from Journal of Animal Science and Biotechnology
#25
of 917 outputs
Outputs of similar age
#46,756
of 423,164 outputs
Outputs of similar age from Journal of Animal Science and Biotechnology
#4
of 20 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 917 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,164 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.