The pan-RAF-MEK non degrading molecular glue NST-628 is a potent and brain penetrant inhibitor of the RAS-MAPK pathway with activity across diverse RAS- and RAF-driven cancers

Overview of attention for article published in Cancer Discovery, April 2024

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In the top 5% of all research outputs scored by Altmetric
Among the highest-scoring outputs from this source (#41 of 4,250)
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So far, Altmetric has seen 126 X posts from 77 X users, with an upper bound of 553,572 followers.

RT @ArndtVogel: The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent & Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with A…

RT @ArndtVogel: The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent & Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with A…

RT @ArndtVogel: The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent & Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with A…

RT @TasukuIshida1: 分解誘導こそしないが、化合物が存在することでRAF-MEKヘテロ４量体の形成を誘導し阻害活性を示す化合物に関する報告。最近Molecular glueやMonovalent degrader関連の研究が盛んで本当にすごい。分子量が小さいの…

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