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The angiotensin II AT1 receptor-associated protein Arap1 is involved in sepsis-induced hypotension

Overview of attention for article published in Critical Care, July 2013
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Title
The angiotensin II AT1 receptor-associated protein Arap1 is involved in sepsis-induced hypotension
Published in
Critical Care, July 2013
DOI 10.1186/cc12809
Pubmed ID
Authors

Katharina Mederle, Frank Schweda, Veronika Kattler, Elisabeth Doblinger, Keishi Miyata, Klaus Höcherl, Yuichi Oike, Hayo Castrop

Abstract

Hypotension in septic patients results from hypovolemia, vasodilatation and hyporeactivity to vasoconstrictors, such as angiotensin II. The AT1 receptor-associated protein 1 (Arap1) is expressed in vascular smooth muscle cells and increases the surface expression of the AT1-receptor in vitro. We hypothesized that dysregulation of Arap1 may contribute to vascular hyporeactivity to angiotensin II during endotoxemia.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 19%
Student > Master 5 14%
Student > Ph. D. Student 5 14%
Other 3 8%
Student > Doctoral Student 2 5%
Other 6 16%
Unknown 9 24%
Readers by discipline Count As %
Medicine and Dentistry 17 46%
Agricultural and Biological Sciences 6 16%
Biochemistry, Genetics and Molecular Biology 4 11%
Computer Science 1 3%
Nursing and Health Professions 1 3%
Other 0 0%
Unknown 8 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2013.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Critical Care
#5,970
of 6,554 outputs
Outputs of similar age
#157,132
of 206,558 outputs
Outputs of similar age from Critical Care
#76
of 100 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
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We're also able to compare this research output to 100 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.