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Prevalence of allergen sensitization in 1000 adults in Saskatchewan

Overview of attention for article published in Allergy, Asthma & Clinical Immunology, February 2017
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Title
Prevalence of allergen sensitization in 1000 adults in Saskatchewan
Published in
Allergy, Asthma & Clinical Immunology, February 2017
DOI 10.1186/s13223-017-0181-1
Pubmed ID
Authors

Stacey D. Lok, Beth E. Davis, Donald W. Cockcroft

Abstract

The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More importantly we aimed to obtain a regional statistic of sensitization to common allergens given Saskatchewan's dry climate. One thousand consecutive symptomatic adults were screened for atopy via skin prick test over 10 years (2006-2016) in the Division of Respirology. An atopic screen was performed with twenty common aeroallergens by a single investigator, Dr. D. Cockcroft. A positive test was considered to be a wheal ≥3 mm and markedly positive reactions ≥8 mm were also documented. The prevalence of atopy by means of a positive skin test (≥3 mm) was 45.5%. The prevalence of one or more markedly positive reactions (≥8 mm) was 29.5% of the total population. The most frequent sensitization was to cat dander (58.2%), followed by mixed grass (32.1%), and birch (26.8%). Dust mite sensitization was 22.4% and mouse 6.2%. A positive epidemiology screen for cat/grass/mite would have incorporated 82.0% (n = 373) of subjects with positive skin tests. Those who failed the cat/grass/mite screen were mainly sensitized to trees (n = 34), molds (n = 22), weeds (n = 7), and animals (n = 8). There is a high prevalence of cat sensitization in Saskatchewan, much higher than recorded in other centers internationally. This is likely due to a high proportion of cat ownership. The prevalence of mite sensitization is lower than those mentioned at other centres likely due to Saskatchewan's dry climate. The significance of the rate of markedly positive reactions (≥8 mm wheal) when compared to humid areas with higher burden of mite is unknown. There is a low prevalence of roach also likely due to the dry climate and mouse sensitization was low but still identified as a significant indoor allergen. A cat/grass/mite screen may be useful with a 82.0% sensitivity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 25%
Other 2 17%
Student > Doctoral Student 1 8%
Unspecified 1 8%
Student > Master 1 8%
Other 1 8%
Unknown 3 25%
Readers by discipline Count As %
Medicine and Dentistry 2 17%
Unspecified 1 8%
Environmental Science 1 8%
Immunology and Microbiology 1 8%
Business, Management and Accounting 1 8%
Other 2 17%
Unknown 4 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Allergy, Asthma & Clinical Immunology
#784
of 924 outputs
Outputs of similar age
#321,956
of 424,548 outputs
Outputs of similar age from Allergy, Asthma & Clinical Immunology
#12
of 15 outputs
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.