Title |
Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids
|
---|---|
Published in |
BMC Pharmacology and Toxicology, January 2017
|
DOI | 10.1186/s40360-016-0111-8 |
Pubmed ID | |
Authors |
Luca Parente |
Abstract |
Deflazacort is a synthetic corticosteroid characterized by a favourable pharmacokinetic profile, peculiar pharmacodynamic properties and a good safety profile. However, to the best of our knowledge, no dose-conversion table based on direct comparison of relative potencies between deflazacort and other main corticosteroids is currently available in scientific literature. This paper, while reporting a brief review of deflazacort pharmacological properties, its efficacy and tolerability in different clinical areas, has been designed with the specific aim of providing a new dose-conversion table of corticosteroids, including for the first time also deflazacort. We suggest that this new conversion table could be a useful tool for physicians who need to select the appropriate dose of deflazacort in their clinical practice. |
X Demographics
Geographical breakdown
Country | Count | As % |
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India | 1 | 33% |
Spain | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 90 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 16 | 18% |
Student > Ph. D. Student | 11 | 12% |
Student > Master | 9 | 10% |
Other | 9 | 10% |
Researcher | 9 | 10% |
Other | 15 | 17% |
Unknown | 21 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 23% |
Pharmacology, Toxicology and Pharmaceutical Science | 12 | 13% |
Biochemistry, Genetics and Molecular Biology | 11 | 12% |
Neuroscience | 6 | 7% |
Chemistry | 5 | 6% |
Other | 9 | 10% |
Unknown | 26 | 29% |