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Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms

Overview of attention for article published in Clinical and Molecular Allergy, February 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)

Mentioned by

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2 tweeters
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1 Facebook page

Citations

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10 Dimensions

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35 Mendeley
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Title
Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms
Published in
Clinical and Molecular Allergy, February 2017
DOI 10.1186/s12948-017-0059-2
Pubmed ID
Authors

Maria Teresa Ventura, Nicola Scichilone, Roberto Paganelli, Paola Lucia Minciullo, Vincenzo Patella, Matteo Bonini, Giovanni Passalacqua, Carlo Lombardi, Livio Simioni, Erminia Ridolo, Stefano R. Del Giacco, Sebastiano Gangemi, Giorgio Walter Canonica

Abstract

Life expectancy and the number of elderly people are progressively increasing around the world. Together with other pathologies, allergic diseases also show an increasing incidence in geriatric age. This is partly due to the growing emphasis on a more accurate and careful diagnosis of the molecular mechanisms that do not allow to ignore the real pathogenesis of many symptoms until now unknown, and partly to the fact that the allergic people from 20 years ago represent the elderly population now. Moreover, environmental pollution predisposes to the onset of allergic asthma and dermatitis which are the result of internal pathologies more than the expression of allergic manifestations. At the same time the food contamination permits the onset of allergic diseases related to food allergy. In this review we provide the state of the art on the physiological changes in the elderly responsible for allergic diseases, their biological characteristics and the major immunological and extra immunological mechanisms. Much emphasis is given to the management of several diseases in the elderly, including anaphylactic reactions. Moreover, some new features are discussed, such as management of asthma with the support of physical activity and the use of the AIT as prevention of respiratory diseases and for the purpose of a real and long lasting benefit. The mechanisms of adverse reactions to drugs are also discussed, due to their frequency in this age, especially in polytherapy regimens. Study of the modifications of the immune system is also of great importance, as regards to the distribution of the lymphocytes and also the presence of a chronic inflammatory disease related to the production of cytokines, especially in prevision of all the possible therapies to be adopted to allow an active and healthy aging.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 11 31%
Researcher 10 29%
Student > Bachelor 10 29%
Student > Ph. D. Student 7 20%
Student > Master 5 14%
Other 19 54%
Readers by discipline Count As %
Medicine and Dentistry 22 63%
Unspecified 13 37%
Biochemistry, Genetics and Molecular Biology 6 17%
Immunology and Microbiology 5 14%
Nursing and Health Professions 4 11%
Other 12 34%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2017.
All research outputs
#6,214,340
of 11,188,694 outputs
Outputs from Clinical and Molecular Allergy
#58
of 111 outputs
Outputs of similar age
#147,561
of 323,853 outputs
Outputs of similar age from Clinical and Molecular Allergy
#1
of 4 outputs
Altmetric has tracked 11,188,694 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 111 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,853 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them