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Distribution of CCR5-Delta32, CCR5 promoter 59029 A/G, CCR2-64I and SDF1-3’A genetic polymorphisms in HIV-1 infected and uninfected patients in the West Region of Cameroon

Overview of attention for article published in BMC Research Notes, July 2013
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Title
Distribution of CCR5-Delta32, CCR5 promoter 59029 A/G, CCR2-64I and SDF1-3’A genetic polymorphisms in HIV-1 infected and uninfected patients in the West Region of Cameroon
Published in
BMC Research Notes, July 2013
DOI 10.1186/1756-0500-6-288
Pubmed ID
Authors

Céline Nguefeu Nkenfou, Linda Chapdeleine Mouafo Mekue, Christelle Tafou Nana, Jules Roger Kuiate

Abstract

Genetic variants of the genes encoding human immunodeficiency virus-1 (HIV-1) co-receptors and their ligands, like CC-chemokine receptor 5 delta 32 mutation (CCR5-Delta32), CCR5 promoter A/G (Adenine/Guanine), CC-chemokine receptor 2 mutation 64 isoleucine (CCR2-64I) and the stromal cell-derived factor 3'A mutation (SDF1-3'A), are involved in the susceptibility to HIV-1 infection and progression. The prevalence of these mutations varies by region. However, little is known about their distribution in the population of Dschang, located in the west region of Cameroon. The prevalence of HIV in the west region of Cameroon is lower than elsewhere in Cameroon. The objectives of this study were to determine the distribution of four AIDS Related Gene (ARG) variants in HIV-infected and non-infected population of Cameroon especially in the west region and to estimate the contribution of these variants to the susceptibility or resistance to HIV infection. We also aimed to evaluate the effectiveness of genotyping using dried blood spot (DBS) samples.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Brazil 1 2%
Unknown 54 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 20%
Student > Ph. D. Student 9 16%
Student > Bachelor 7 13%
Student > Doctoral Student 7 13%
Student > Postgraduate 5 9%
Other 9 16%
Unknown 8 14%
Readers by discipline Count As %
Medicine and Dentistry 14 25%
Agricultural and Biological Sciences 13 23%
Biochemistry, Genetics and Molecular Biology 8 14%
Nursing and Health Professions 5 9%
Social Sciences 2 4%
Other 4 7%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2013.
All research outputs
#17,691,177
of 22,714,025 outputs
Outputs from BMC Research Notes
#2,823
of 4,257 outputs
Outputs of similar age
#142,197
of 197,837 outputs
Outputs of similar age from BMC Research Notes
#43
of 58 outputs
Altmetric has tracked 22,714,025 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,257 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,837 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.