Title |
UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial
|
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Published in |
Trials, April 2012
|
DOI | 10.1186/1745-6215-13-51 |
Pubmed ID | |
Authors |
Fiona F Craig, Kim S Thomas, Eleanor J Mitchell, Hywel C Williams, John Norrie, James M Mason, Anthony D Ormerod |
Abstract |
Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder characterised by painful and rapidly progressing skin ulceration. PG can be extremely difficult to treat and patients often require systemic immunosuppression. Recurrent lesions of PG are common, but the relative rarity of this condition means that there is a lack of published evidence regarding its treatment. A systematic review published in 2005 found no randomised controlled trials (RCTs) relating to the treatment of PG. Since this time, one small RCT has been published comparing infliximab to placebo, but none of the commonly used systemic treatments for PG have been formally assessed. The UK Dermatology Clinical Trials Network's STOP GAP Trial has been designed to address this lack of trial evidence. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
Colombia | 1 | <1% |
Unknown | 104 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 14% |
Student > Master | 15 | 14% |
Researcher | 12 | 11% |
Student > Bachelor | 9 | 8% |
Student > Doctoral Student | 8 | 8% |
Other | 23 | 22% |
Unknown | 24 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 59 | 56% |
Nursing and Health Professions | 5 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Unspecified | 2 | 2% |
Immunology and Microbiology | 1 | <1% |
Other | 9 | 8% |
Unknown | 26 | 25% |